Detail Information for IndEnz0001000044
IED ID IndEnz0001000044
Enzyme Type ID amylase000044
Protein Name Alpha-glucosidase MAL12
EC 3.2.1.20
Maltase
Gene Name MAL12 MAL1S YGR292W
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Saccharomycetaceae Saccharomyces Saccharomyces cerevisiae (Baker's yeast) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Enzyme Sequence MTISDHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHPNWGSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDNALYTSAARYEVSEVFSFTHVEVGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSFGKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFLLNESFEQGINVEQESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYEDKTLFAALNFSGEEIEFSLPREGASLSFILGNYDDTDVSSRVLKPWEGRIYLVK
Enzyme Length 584
Uniprot Accession Number P53341
Absorption
Active Site ACT_SITE 214; /note=Nucleophile; /evidence=ECO:0000250; ACT_SITE 276; /note=Proton donor; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.; EC=3.2.1.20;
DNA Binding
EC Number 3.2.1.20
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Site (1)
Keywords Glycosidase;Hydrolase;Maltose metabolism;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 11283351; 11805826; 15291818; 15588703; 17671744; 19418260; 19536198; 19824618; 20443596; 20471265; 20518737; 20562106; 20827790; 20832886; 22307809; 22583100; 23239941; 23455612; 24457149; 27714848; 2851483; 3025617; 3323827; 374342; 6338938; 6355759; 6387396; 7034722; 7045078; 7839734; 9037205; 9301020;
Motif
Gene Encoded By
Mass 68,094
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda 2.4.1.B65;3.2.1.20;