Detail Information for IndEnz0001000186
IED ID IndEnz0001000186
Enzyme Type ID amylase000186
Protein Name Catabolite control protein A
Catabolite control protein
Glucose-resistance amylase regulator
Gene Name ccpA
Organism Priestia megaterium (Bacillus megaterium)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Bacillaceae Priestia Priestia megaterium (Bacillus megaterium)
Enzyme Sequence MNVTIYDVAREASVSMATVSRVVNGNPNVKPSTRKKVLETIERLGYRPNAVARGLASKKTTTVGVIIPDISNIFYAELARGIEDIATMYKYNIILSNSDQNQDKELHLLNNMLGKQVDGIIFMSGNVTEEHVEELKKSPVPVVLAASIESTNQIPSVTIDYEQAAFDAVQSLIDSGHKNIAFVSGTLEEPINHAKKVKGYKRALTESGLPVRDSYIVEGDYTYDSGIEAVEKLLEEDEKPTAIFVGTDEMALGVIHGAQDRGLNVPNDLEIIGFDNTRLSTMVRPQLTSVVQPMYDIGAVAMRLLTKYMNKETVDSSIVQLPHRIEFRQSTK
Enzyme Length 332
Uniprot Accession Number P46828
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding DNA_BIND 5..24; /note=H-T-H motif; /evidence=ECO:0000255|PROSITE-ProRule:PRU00111
EC Number
Enzyme Function FUNCTION: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Beta strand (17); Chain (1); DNA binding (1); Domain (1); Helix (16); Turn (3)
Keywords 3D-structure;Activator;DNA-binding;Repressor;Transcription;Transcription regulation
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D X-ray crystallography (9)
Cross Reference PDB 1RZR; 1SXG; 1SXH; 1SXI; 2HSG; 2JCG; 2NZU; 2NZV; 2OEN;
Mapped Pubmed ID 10666630; 15369672; 17376479; 17401189; 17500051;
Motif
Gene Encoded By
Mass 36,645
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda