| IED ID | IndEnz0001000496 |
| Enzyme Type ID | amylase000496 |
| Protein Name |
Transcription factor MYB4 Myb-related protein 4 CcMYB4 |
| Gene Name | MYB4 |
| Organism | Crocosmia x crocosmiiflora (Montbretia) (Crocosmia aurea x Crocosmia pottsii) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae Liliopsida Petrosaviidae Asparagales Iridaceae Crocoideae Freesieae Crocosmia Crocosmia x crocosmiiflora (Montbretia) (Crocosmia aurea x Crocosmia pottsii) |
| Enzyme Sequence | MVKRSQRVEKKAVEVNRGTWTAEEDEKLMNYVSAHGDKKWRMLPAKAGLKRCGKSCRLRWLNYLRPGIKRGNISEDEEDLIIRLHNLLGNRWSIIAGRIPGRTDNEIKNHWNTHLSKRSLTIEDLNKKHNPGIDNIDILPPTKITLTSSSDTFPVTPVCQTDQASDTNKNDVLVDSWTDLSGPDFDLEQFLSLLPMSDLCPGSNGNELEFDDFGIPRHDSKQDSFRSNDYNINYQECLDSQVWSCAFEYDDLDQFLDCQS |
| Enzyme Length | 260 |
| Uniprot Accession Number | A0A4D6Q5I0 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | DNA_BIND 40..64; /note=H-T-H motif; /evidence=ECO:0000255|PROSITE-ProRule:PRU00625; DNA_BIND 92..115; /note=H-T-H motif; /evidence=ECO:0000255|PROSITE-ProRule:PRU00625 |
| EC Number | |
| Enzyme Function | FUNCTION: Transcription activator involved in the spatiotemporal regulation of flavonoid biosynthesis specifically in the corms of Montbretia (PubMed:31004005). Activates the promoters of enzymes involved in the biosynthesis of the flavonol myricetin and the flavonol-glycoside montbretin A (MbA) (PubMed:31004005). MbA is a potent inhibitor of human pancreatic alpha-amylase and is being developed as drug candidate to treat type-2 diabetes (PubMed:31004005). {ECO:0000269|PubMed:31004005}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); DNA binding (2); Domain (2) |
| Keywords | Activator;DNA-binding;Nucleus;Repeat;Transcription;Transcription regulation |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 29,821 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |