Detail Information for IndEnz0001000919
IED ID IndEnz0001000919
Enzyme Type ID amylase000919
Protein Name Cholecystokinin
CCK
Gene Name CCK
Organism Dasyurus viverrinus (Eastern quoll) (Didelphis viverrina)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Metatheria Dasyuromorphia Dasyuridae Dasyurus (quolls) Dasyurus viverrinus (Eastern quoll) (Didelphis viverrina)
Enzyme Sequence DYMGWMDF
Enzyme Length 8
Uniprot Accession Number P68125
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Modified residue (2); Peptide (1)
Keywords Amidation;Direct protein sequencing;Hormone;Secreted;Sulfation
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted.
Modified Residue MOD_RES 2; /note=Sulfotyrosine; /evidence=ECO:0000269|PubMed:3375140; MOD_RES 8; /note=Phenylalanine amide; /evidence=ECO:0000269|PubMed:3375140
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 1,064
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda