| IED ID | IndEnz0001000920 |
| Enzyme Type ID | amylase000920 |
| Protein Name |
Cholecystokinin CCK |
| Gene Name | CCK |
| Organism | Macropus giganteus (Eastern gray kangaroo) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Metatheria Diprotodontia Macropodidae Macropus Macropus giganteus (Eastern gray kangaroo) |
| Enzyme Sequence | DYMGWMDF |
| Enzyme Length | 8 |
| Uniprot Accession Number | P0C229 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Modified residue (2); Peptide (1) |
| Keywords | Amidation;Direct protein sequencing;Hormone;Secreted;Sulfation |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted. |
| Modified Residue | MOD_RES 2; /note=Sulfotyrosine; /evidence=ECO:0000269|PubMed:8134294; MOD_RES 8; /note=Phenylalanine amide; /evidence=ECO:0000269|PubMed:8134294 |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 1,064 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |