| IED ID | IndEnz0002000061 |
| Enzyme Type ID | protease000061 |
| Protein Name |
Metacaspase-1 EC 3.4.22.- |
| Gene Name | casA AN5712 |
| Organism | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Nidulantes Emericella nidulans (Aspergillus nidulans) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
| Enzyme Sequence | MHHHHQQPSYGSGYPGQAYRQQQNPYPQYGHPSPQPYPPQNGYSHPSSGYPPSPAPPNGGQMYHGRQPSYPPNQYPPAHGGPTAPPTNPQAFGHGAPQGYNFQYSRCTGKRKALLIGINYFGQKGQLRGCINDVKNMSTYLNQNFGYAREDMVILTDDQQNPMSQPTKANILRAMHWLVKDAQPNDSLFFHYSGHGGQTPDLDGDEDDGYDEVIYPVDFRVAGHIVDDEMHRIMVKPLQPGVRLTAIFDSCHSGSALDLPYIYSTQGILKEPNLAKEAGQGLLGVISSYARGDMGGMMSTAVGFLKKAAKGDEAYQRTKQTKTSPADVIMWSGSKDDQTSQDAQIAGQATGAMSWAFITAMRKNPQQSYVQLLNSIRDELSTRYTQKPQLSSSHPLDVNLLYVM |
| Enzyme Length | 404 |
| Uniprot Accession Number | Q8J140 |
| Absorption | |
| Active Site | ACT_SITE 195; /evidence=ECO:0000250; ACT_SITE 251; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | FUNCTION: Involved in cell death (apoptosis). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Compositional bias (2); Erroneous gene model prediction (1); Propeptide (1); Region (1) |
| Keywords | Apoptosis;Hydrolase;Protease;Reference proteome;Thiol protease;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 44,598 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |