IED ID | IndEnz0002000145 |
Enzyme Type ID | protease000145 |
Protein Name |
Peptidase B EC 3.4.11.23 Aminopeptidase B |
Gene Name | pepB VS_0614 |
Organism | Vibrio atlanticus (strain LGP32) (Vibrio splendidus (strain Mel32)) |
Taxonomic Lineage | cellular organisms Bacteria Proteobacteria Gammaproteobacteria Vibrionales Vibrionaceae Vibrio Vibrio atlanticus Vibrio atlanticus (strain LGP32) (Vibrio splendidus (strain Mel32)) |
Enzyme Sequence | MSTQMSVFLSQEAAQPQWGARAILSFSEAGATIHIGEGHDLGAVQRAGRTLDGQGIALVALSGKGWDLESVWAFYQGYRGPKKKNALEWDALAEADQVELEARIRATDWTRDIINKTAEEVAPRQLATMAAEYIKSVAPAGTVKAKIVKDKDLLTEGWEGIYAVGRGSERTSAMLQLDFNPTGDENAPVFACLVGKGITFDSGGYSIKPGQFMTAMKADMGGAATITGGLGLAIERGLNKRIKLILCCAENMISGRALKLGDIITYKNGKTVEIMNTDAEGRLVLADGLMFASAQNPELIIDCATLTGAAKNALGNDYHALLSFDDELSHQALTAANQEKEGLWPLPLADFHRGMLPSNFADLSNISSGDYTPGASTAAAFLSYFVDDYKKGWIHMDCAGTYRKSSSDKWAAGATGMGVRTLARLLIDQAK |
Enzyme Length | 431 |
Uniprot Accession Number | B7VJT3 |
Absorption | |
Active Site | ACT_SITE 208; /evidence=ECO:0000255|HAMAP-Rule:MF_00504; ACT_SITE 282; /evidence=ECO:0000255|HAMAP-Rule:MF_00504 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | CATALYTIC ACTIVITY: Reaction=Release of an N-terminal amino acid, Xaa, from a peptide or arylamide. Xaa is preferably Glu or Asp but may be other amino acids, including Leu, Met, His, Cys and Gln.; EC=3.4.11.23; Evidence={ECO:0000255|HAMAP-Rule:MF_00504}; |
DNA Binding | |
EC Number | 3.4.11.23 |
Enzyme Function | FUNCTION: Probably plays an important role in intracellular peptide degradation. {ECO:0000255|HAMAP-Rule:MF_00504}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (2); Chain (1); Metal binding (7) |
Keywords | Aminopeptidase;Cytoplasm;Hydrolase;Manganese;Metal-binding;Protease;Reference proteome |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00504}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 46,144 |
Kinetics | |
Metal Binding | METAL 196; /note=Manganese 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00504; METAL 201; /note=Manganese 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00504; METAL 201; /note=Manganese 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00504; METAL 219; /note=Manganese 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00504; METAL 278; /note=Manganese 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00504; METAL 280; /note=Manganese 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00504; METAL 280; /note=Manganese 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00504 |
Rhea ID | |
Cross Reference Brenda |