Detail Information for IndEnz0002000383
IED ID IndEnz0002000383
Enzyme Type ID protease000383
Protein Name Xaa-Pro dipeptidase
X-Pro dipeptidase
EC 3.4.13.9
Imidodipeptidase
Proline dipeptidase
Prolidase
Gene Name pepQ SbBS512_E4317
Organism Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Gammaproteobacteria Enterobacterales Enterobacteriaceae Shigella Shigella boydii Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)
Enzyme Sequence MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHASVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHLQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFSGIRIEDNVVIHENNVENMTRDLKLA
Enzyme Length 443
Uniprot Accession Number B2TVJ6
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Hydrolysis of Xaa-|-Pro dipeptides. Also acts on aminoacyl-hydroxyproline analogs. No action on Pro-|-Pro.; EC=3.4.13.9; Evidence={ECO:0000255|HAMAP-Rule:MF_01279};
DNA Binding
EC Number 3.4.13.9
Enzyme Function FUNCTION: Splits dipeptides with a prolyl residue in the C-terminal position. {ECO:0000255|HAMAP-Rule:MF_01279}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Metal binding (7)
Keywords Dipeptidase;Hydrolase;Manganese;Metal-binding;Metalloprotease;Protease
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 50,222
Kinetics
Metal Binding METAL 246; /note=Manganese 2; /evidence=ECO:0000255|HAMAP-Rule:MF_01279; METAL 257; /note=Manganese 1; /evidence=ECO:0000255|HAMAP-Rule:MF_01279; METAL 257; /note=Manganese 2; /evidence=ECO:0000255|HAMAP-Rule:MF_01279; METAL 339; /note=Manganese 1; /evidence=ECO:0000255|HAMAP-Rule:MF_01279; METAL 384; /note=Manganese 1; /evidence=ECO:0000255|HAMAP-Rule:MF_01279; METAL 423; /note=Manganese 1; /evidence=ECO:0000255|HAMAP-Rule:MF_01279; METAL 423; /note=Manganese 2; /evidence=ECO:0000255|HAMAP-Rule:MF_01279
Rhea ID
Cross Reference Brenda