Detail Information for IndEnz0002000395
IED ID IndEnz0002000395
Enzyme Type ID protease000395
Protein Name Xaa-Pro dipeptidase
X-Pro dipeptidase
EC 3.4.13.9
Imidodipeptidase
Proline dipeptidase
Prolidase
Gene Name pepQ Smlt3861
Organism Stenotrophomonas maltophilia (strain K279a)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Gammaproteobacteria Xanthomonadales Xanthomonadaceae Stenotrophomonas Stenotrophomonas maltophilia group Stenotrophomonas maltophilia (Pseudomonas maltophilia) (Xanthomonas maltophilia) Stenotrophomonas maltophilia (strain K279a)
Enzyme Sequence MIQQDPGALYSDHLAVLCRRAEQALARGGFDHLVVPSGTLHYQVFDDRDYPYAVNPQFKAWLPLTRVPNSWIVFTPGKRPAVIFHQPFDYWHVVPDAPSGWWVEHFDIHIIRKPEEALALLPADPSRCAILGEPQSALGNYVPNNPAPVVNYLEWHRGSKTPYEIALMRQAQVLGVRGHRAAEAAFRNGADEFSIHMAYCQAVGQDANELPYGNIVALNEHAAVLHYTELGRKAPQPLRSFLIDAGASAHGYASDITRTYAAQGHDEFAAMIAAVDAAQQQMCAAVRPGFDYKQLHVDAHLSLMGVLKDFGVIKVSPQTALETGVSAAFFPHGIGHLIGLQVHDVAGFAASDEGGRIERPAGHPYLRLTRVLEPGMVVTIEPGLYFIDMLLNEVKDAGHGDAINWERVDFFRPYGGIRIEDEVLCTDGEADNLTRPAFAAANG
Enzyme Length 443
Uniprot Accession Number B2FT23
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Hydrolysis of Xaa-|-Pro dipeptides. Also acts on aminoacyl-hydroxyproline analogs. No action on Pro-|-Pro.; EC=3.4.13.9; Evidence={ECO:0000255|HAMAP-Rule:MF_01279};
DNA Binding
EC Number 3.4.13.9
Enzyme Function FUNCTION: Splits dipeptides with a prolyl residue in the C-terminal position. {ECO:0000255|HAMAP-Rule:MF_01279}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Metal binding (7)
Keywords Dipeptidase;Hydrolase;Manganese;Metal-binding;Metalloprotease;Protease;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 48,678
Kinetics
Metal Binding METAL 244; /note=Manganese 2; /evidence=ECO:0000255|HAMAP-Rule:MF_01279; METAL 255; /note=Manganese 1; /evidence=ECO:0000255|HAMAP-Rule:MF_01279; METAL 255; /note=Manganese 2; /evidence=ECO:0000255|HAMAP-Rule:MF_01279; METAL 336; /note=Manganese 1; /evidence=ECO:0000255|HAMAP-Rule:MF_01279; METAL 381; /note=Manganese 1; /evidence=ECO:0000255|HAMAP-Rule:MF_01279; METAL 420; /note=Manganese 1; /evidence=ECO:0000255|HAMAP-Rule:MF_01279; METAL 420; /note=Manganese 2; /evidence=ECO:0000255|HAMAP-Rule:MF_01279
Rhea ID
Cross Reference Brenda