| IED ID | IndEnz0002000433 |
| Enzyme Type ID | protease000433 |
| Protein Name |
Peptidase 1 EC 3.4.22.65 Allergen Eur m I Mite group 1 allergen Eur m 1 allergen Eur m 1 |
| Gene Name | EURM1 |
| Organism | Euroglyphus maynei (Mayne's house dust mite) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Chelicerata Arachnida Acari Acariformes Sarcoptiformes Astigmata Psoroptidia Analgoidea (feather mites) Pyroglyphidae (house-dust mites) Pyroglyphinae Euroglyphus Euroglyphus maynei (Mayne's house dust mite) |
| Enzyme Sequence | MKIILAIASLLVLSAVYARPASIKTFEEFKKAFNKTYATPEKEEVARKNFLESLKYVESNKGAINHLSDLSLDEFKNQFLMNANAFEQLKTQFDLNAETYACSINSVSLPSELDLRSLRTVTPIRMQGGCGSCWAFSGVASTESAYLAYRNMSLDLAEQELVDCASQNGCHGDTIPRGIEYIQQNGVVQEHYYPYVAREQSCHRPNAQRYGLKNYCQISPPDSNKIRQALTQTHTAVAVIIGIKDLNAFRHYDGRTIMQHDNGYQPNYHAVNIVGYGNTQGVDYWIVRNSWDTTWGDNGYGYFAANINLMMIEQYPYVVML |
| Enzyme Length | 321 |
| Uniprot Accession Number | P25780 |
| Absorption | |
| Active Site | ACT_SITE 133; /evidence=ECO:0000250; ACT_SITE 269; /evidence=ECO:0000250; ACT_SITE 289; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Broad endopeptidase specificity.; EC=3.4.22.65; |
| DNA Binding | |
| EC Number | 3.4.22.65 |
| Enzyme Function | FUNCTION: Probable thiol protease. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (1); Erroneous initiation (1); Glycosylation (2); Natural variant (3); Propeptide (1); Signal peptide (1) |
| Keywords | Allergen;Disulfide bond;Glycoprotein;Hydrolase;Protease;Secreted;Signal;Thiol protease;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..18; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 36,290 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |