| IED ID | IndEnz0002000435 |
| Enzyme Type ID | protease000435 |
| Protein Name |
Pepsin-2B EC 3.4.23.- Pepsin IIB |
| Gene Name | |
| Organism | Gadus morhua (Atlantic cod) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Actinopterygii Actinopteri Neopterygii Teleostei Osteoglossocephalai Clupeocephala Euteleosteomorpha Neoteleostei Eurypterygia Ctenosquamata Acanthomorphata Paracanthopterygii Zeiogadaria Gadariae Gadiformes (cods and others) Gadoidei Gadidae (cods) Gadus Gadus morhua (Atlantic cod) |
| Enzyme Sequence | RVTEQMKNEADTEYYGVISIGTPPESFKVIFDTGSSNLWVSSSHCSAQACSNHNKFKPRQSSTYVETGKTVDLTYGTGGMRGILGQDTVSVGGGSDPNQELGESQTEPGPFQAAAPFDGILGLAYPSIAAAGAVPVFDNMGSQSLVEKDLFSFYLSGGGANGSEVMLGGVDNSHYTGSIHWIPVTAEKYWQVALDGITVNGQTAACEGCQAIVDTGTSKIVAPVSALANIMKDIGASENQGEMMGNCASVQSLPDITFTINGVKQPLPPSAYIEGDQAFCTSGLGSSGVPSNTSELWIFGDVFLRNYYTIYDRTNNKVGFAPAA |
| Enzyme Length | 324 |
| Uniprot Accession Number | P56272 |
| Absorption | |
| Active Site | ACT_SITE 32; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094; ACT_SITE 214; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.23.- |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Beta strand (25); Chain (1); Compositional bias (1); Disulfide bond (3); Domain (1); Helix (9); Region (1); Turn (6) |
| Keywords | 3D-structure;Aspartyl protease;Digestion;Direct protein sequencing;Disulfide bond;Hydrolase;Protease |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | X-ray crystallography (1) |
| Cross Reference PDB | 1AM5; |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 34,014 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |