Detail Information for IndEnz0002000505
IED ID IndEnz0002000505
Enzyme Type ID protease000505
Protein Name Peptidase T
EC 3.4.11.4
Aminotripeptidase
Tripeptidase
Tripeptide aminopeptidase
Gene Name pepT DSY2060
Organism Desulfitobacterium hafniense (strain Y51)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Firmicutes Clostridia Eubacteriales Peptococcaceae Desulfitobacterium Desulfitobacterium hafniense (Desulfitobacterium frappieri) Desulfitobacterium hafniense (strain Y51)
Enzyme Sequence MSSVIERFLRYVAIDTQSNEESQTTPSTGKQLNLARLLEQELKELGLQDARIQEGYVYGTLPANSTKAIPAIGFIAHMDTSPDFSGTNVKAQLVENYDGQDILLNPEHNLVLSPADFPELLDYIGKTLITTDGTTLLGADDKAGIAEIMTAIAYLTAHPEIEHGTICVAFTPDEEIGRGADQFDVAGFGADFAYTVDGGPIGELEYENFNAAKAIVKVKGRNVHPGNAKNKMINSILLANEYIVKLPPQETPATTEGYEGFYHLNDIRGDVEETTLYYIIRDFAEDSFAKRKETMLNLAEECNKKYGSGHFHVEITDQYKNMKEKIQPVMHIVDKAQKAMETVGVKPLIKPIRGGTDGSRLSFMGLPTPNLFTGGHNYHGRYEFIPTFAMEKSVEVILKIIELYAEEHSN
Enzyme Length 410
Uniprot Accession Number Q24VU3
Absorption
Active Site ACT_SITE 79; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; ACT_SITE 174; /note=Proton acceptor; /evidence=ECO:0000255|HAMAP-Rule:MF_00550
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Release of the N-terminal residue from a tripeptide.; EC=3.4.11.4; Evidence={ECO:0000255|HAMAP-Rule:MF_00550};
DNA Binding
EC Number 3.4.11.4
Enzyme Function FUNCTION: Cleaves the N-terminal amino acid of tripeptides. {ECO:0000255|HAMAP-Rule:MF_00550}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Metal binding (6)
Keywords Aminopeptidase;Cytoplasm;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00550}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 45,390
Kinetics
Metal Binding METAL 77; /note=Zinc 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 140; /note=Zinc 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 140; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 175; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 197; /note=Zinc 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 379; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00550
Rhea ID
Cross Reference Brenda