Detail Information for IndEnz0002000577
IED ID IndEnz0002000577
Enzyme Type ID protease000577
Protein Name Peptidase T
EC 3.4.11.4
Aminotripeptidase
Tripeptidase
Tripeptide aminopeptidase
Gene Name pepT CGSHiGG_00385
Organism Haemophilus influenzae (strain PittGG)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Gammaproteobacteria Pasteurellales Pasteurellaceae Haemophilus Haemophilus influenzae Haemophilus influenzae (strain PittGG)
Enzyme Sequence MISQIDKTELLERFLHYVSFHTQSKPHAKHSPSSVGQMKLAMQLQKELIQLGLENVEVSKYAVVTAFLPANDPNLTKTIGLVAHLDTSPQCSGKNVRPEVIEEYRGGDIALGIGEEFISPVYYSFMQKLVGQTLIVTDGTTLLGADNKAGIAEIMTALSILQKENIPHCNIRVAFTPDEEIGLGIHYFPMEKFSCDWAYTIDGGEVGELEYENFNAATAKVRFFGRNIHTGYAKGKMLNALTLACEFQQVFPVDEVPEKTDGKVGFYHLEDFSGDIEQVELTYLIRDFDEQNFAQRKAFIKNQVEKFNAKKGLKKPIELEIQDSYQNMYDVVKNVPQSIELADRAMKAVGIKPNHKPIRGGTDGAFLASKGLACPNIFTGGYNFHSKHELVSLQGMENTVQVIIEMLKCKDL
Enzyme Length 412
Uniprot Accession Number A5UEI5
Absorption
Active Site ACT_SITE 86; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; ACT_SITE 179; /note=Proton acceptor; /evidence=ECO:0000255|HAMAP-Rule:MF_00550
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Release of the N-terminal residue from a tripeptide.; EC=3.4.11.4; Evidence={ECO:0000255|HAMAP-Rule:MF_00550};
DNA Binding
EC Number 3.4.11.4
Enzyme Function FUNCTION: Cleaves the N-terminal amino acid of tripeptides. {ECO:0000255|HAMAP-Rule:MF_00550}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Metal binding (6)
Keywords Aminopeptidase;Cytoplasm;Hydrolase;Metal-binding;Metalloprotease;Protease;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00550}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 46,009
Kinetics
Metal Binding METAL 84; /note=Zinc 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 146; /note=Zinc 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 146; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 180; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 202; /note=Zinc 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 385; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00550
Rhea ID
Cross Reference Brenda