Detail Information for IndEnz0002000606
IED ID IndEnz0002000606
Enzyme Type ID protease000606
Protein Name Peptidase T
EC 3.4.11.4
Aminotripeptidase
Tripeptidase
Tripeptide aminopeptidase
Gene Name pepT LACR_1996
Organism Lactococcus lactis subsp. cremoris (strain SK11)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Lactobacillales Streptococcaceae Lactococcus (lactic streptococci) Lactococcus lactis subsp. cremoris (Streptococcus cremoris) Lactococcus cremoris subsp. cremoris Lactococcus lactis subsp. cremoris (strain SK11)
Enzyme Sequence MKYEKLLPRFLEYVKVNTRSDENSTTTPSTQALVEFAHKMGEDMKALGLKDVHYLESNGYVIGTIPANTDKKVRKIGLLAHLDTADFNAEGVNPQILENYDGESVIQLGDTEFTLDPKDFPNLKNYKGQTLVHTDGTTLLGSDDKSGVAEIMTLADYLLNINPDFEHGEIRVGFGPDEEIGVGADKFDVADFDVDFAYTVDGGPLGELQYETFSAAGAVIEFQGKNVHPGTAKNMMVNALQLAIDYHNALPEFDRPEKTEGREGFFHLLKLDGTPEEARAQYIIRDHEEGKFNERKALMQEIADKMNAELGQNRVKPVIKDQYYNMAQIIEKDMSIIDIAKKAMENLDIAPIIEPIRGGTDGSKISFMGLPTPNLFAGGENMHGRFEFVSVQTMEKAVDTLLEIIRLNNEVAK
Enzyme Length 413
Uniprot Accession Number Q02X44
Absorption
Active Site ACT_SITE 83; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; ACT_SITE 178; /note=Proton acceptor; /evidence=ECO:0000255|HAMAP-Rule:MF_00550
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Release of the N-terminal residue from a tripeptide.; EC=3.4.11.4; Evidence={ECO:0000255|HAMAP-Rule:MF_00550};
DNA Binding
EC Number 3.4.11.4
Enzyme Function FUNCTION: Cleaves the N-terminal amino acid of tripeptides. {ECO:0000255|HAMAP-Rule:MF_00550}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Metal binding (6)
Keywords Aminopeptidase;Cytoplasm;Hydrolase;Metal-binding;Metalloprotease;Protease;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00550}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 45,946
Kinetics
Metal Binding METAL 81; /note=Zinc 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 143; /note=Zinc 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 143; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 179; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 201; /note=Zinc 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 383; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00550
Rhea ID
Cross Reference Brenda