Detail Information for IndEnz0002000629
IED ID IndEnz0002000629
Enzyme Type ID protease000629
Protein Name Peptidase T
EC 3.4.11.4
Aminotripeptidase
Tripeptidase
Tripeptide aminopeptidase
Gene Name pepT LMHCC_0782
Organism Listeria monocytogenes serotype 4a (strain HCC23)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Listeriaceae Listeria Listeria monocytogenes Listeria monocytogenes serotype 4a (strain HCC23)
Enzyme Sequence MKEELLKRFTKYVKVDTQSNEESTVCPTTPGQMELANILVTELKEIGMQEVTVDEFGYVMATLPSNTTKEVPVIGFLAHLDTATDLTGKNVQPQVHENYDGKDIVLNKDLNVVLSPKQFPELADYKGKTLITTDGTTLLGADDKAGITEIMVAMNYLINHPEIKHGKIRVAFTPDEEIGRGPERFDVEAFGAKYAYTMDGGPLGELEYESFNAAGAKITFNGNSVHPGTAKNKMVNAVKMAMEFNARIPKDEAPEYTEGYEGFYHLISLNGDVEQAKAYYIIRDFDHLKFVERKTHIASIAKELEEKYGEGSVELKLNDQYYNMREKIEPVKEIVDIVSAAMRNLDIEPKISPIRGGTDGAQLSYKGLPTPNIFGGGENFHGKFEYVALESMVKATEVIIEVARLFEEKE
Enzyme Length 410
Uniprot Accession Number B8DDX7
Absorption
Active Site ACT_SITE 81; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; ACT_SITE 176; /note=Proton acceptor; /evidence=ECO:0000255|HAMAP-Rule:MF_00550
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Release of the N-terminal residue from a tripeptide.; EC=3.4.11.4; Evidence={ECO:0000255|HAMAP-Rule:MF_00550};
DNA Binding
EC Number 3.4.11.4
Enzyme Function FUNCTION: Cleaves the N-terminal amino acid of tripeptides. {ECO:0000255|HAMAP-Rule:MF_00550}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Metal binding (6)
Keywords Aminopeptidase;Cytoplasm;Hydrolase;Metal-binding;Metalloprotease;Protease;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00550}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 45,715
Kinetics
Metal Binding METAL 79; /note=Zinc 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 142; /note=Zinc 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 142; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 177; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 199; /note=Zinc 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 381; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00550
Rhea ID
Cross Reference Brenda