Detail Information for IndEnz0002000731
IED ID IndEnz0002000731
Enzyme Type ID protease000731
Protein Name Peptidase T
EC 3.4.11.4
Aminotripeptidase
Tripeptidase
Tripeptide aminopeptidase
Gene Name pepT SAS0708
Organism Staphylococcus aureus (strain MSSA476)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Staphylococcaceae Staphylococcus Staphylococcus aureus Staphylococcus aureus (strain MSSA476)
Enzyme Sequence MKNQLIDRLTRYTTIDTQSDPKSTTTPSTEKQWDLLHLLEKELQQLGLPTDLDENGYLFATLESNIDVDVPTVGFLAHVDTSPDFNASNVKPQIIENYDGKPYKLGNTKRVLDPKVFPELNSLVGHTLMVTDGTSLLGADDKAGIVEIMEAICYLQEHPEIKHGTIRIGFTPDEEIGRGPHKFDVDRFNADFAYTMDGSQYGELQYESFNAAEAVITCHGVNVHPGSAKNAMVNAIRLGEQFDSLLPDSEVPERTEGYEGFYHLMNFEGTVEKATLQYIIRDHDKKQFELRKKRILEIRDDINAHFENYPVKVDISDQYFNMAEKILPLPHIIDIPKRVFAKLDIPANTEPIRGGTDGSQLSFMGLPTPNIFTGCGNFHGPYEYASIDVMEKAVQVIIGIVEDIAENH
Enzyme Length 408
Uniprot Accession Number Q6GB87
Absorption
Active Site ACT_SITE 80; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; ACT_SITE 174; /note=Proton acceptor; /evidence=ECO:0000255|HAMAP-Rule:MF_00550
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Release of the N-terminal residue from a tripeptide.; EC=3.4.11.4; Evidence={ECO:0000255|HAMAP-Rule:MF_00550};
DNA Binding
EC Number 3.4.11.4
Enzyme Function FUNCTION: Cleaves the N-terminal amino acid of tripeptides. {ECO:0000255|HAMAP-Rule:MF_00550}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Metal binding (6); Region (1)
Keywords Aminopeptidase;Cytoplasm;Hydrolase;Metal-binding;Metalloprotease;Protease;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00550}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 45,848
Kinetics
Metal Binding METAL 78; /note=Zinc 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 140; /note=Zinc 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 140; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 175; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 197; /note=Zinc 1; /evidence=ECO:0000255|HAMAP-Rule:MF_00550; METAL 379; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_00550
Rhea ID
Cross Reference Brenda