| IED ID | IndEnz0002000778 |
| Enzyme Type ID | protease000778 |
| Protein Name |
Aspartic proteinase PCS1 EC 3.4.23.- Aspartic protease 38 AtASP38 Protein EMBRYO DEFECTIVE 24 Protein PROMOTION OF CELL SURVIVAL 1 |
| Gene Name | PCS1 EMB24 At5g02190 T7H20.240 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MFSRFHALFLLLVLSVRTYKCVSSSSSSSSSFSFSSFSSSSSSQTLVLPLKTRITPTDHRPTDKLHFHHNVTLTVTLTVGTPPQNISMVIDTGSELSWLRCNRSSNPNPVNNFDPTRSSSYSPIPCSSPTCRTRTRDFLIPASCDSDKLCHATLSYADASSSEGNLAAEIFHFGNSTNDSNLIFGCMGSVSGSDPEEDTKTTGLLGMNRGSLSFISQMGFPKFSYCISGTDDFPGFLLLGDSNFTWLTPLNYTPLIRISTPLPYFDRVAYTVQLTGIKVNGKLLPIPKSVLVPDHTGAGQTMVDSGTQFTFLLGPVYTALRSHFLNRTNGILTVYEDPDFVFQGTMDLCYRISPVRIRSGILHRLPTVSLVFEGAEIAVSGQPLLYRVPHLTVGNDSVYCFTFGNSDLMGMEAYVIGHHHQQNMWIEFDLQRSRIGLAPVECDVSGQRLGIGS |
| Enzyme Length | 453 |
| Uniprot Accession Number | Q9LZL3 |
| Absorption | |
| Active Site | ACT_SITE 91; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094; ACT_SITE 304; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.23.- |
| Enzyme Function | FUNCTION: Embryo-specific aspartic protease that limits programmed cell death during reproductive development. Possesses peptidase activity toward casein in vitro. {ECO:0000269|PubMed:15723040}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Domain (1); Glycosylation (8); Propeptide (1); Signal peptide (1) |
| Keywords | Aspartyl protease;Endoplasmic reticulum;Glycoprotein;Hydrolase;Protease;Reference proteome;Signal;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Endoplasmic reticulum. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..18; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 10807919; 14576160; 14697270; 15809863; 16489135; 19653625; 19765857; 19812694; 20304971; 20381898; 24232790; 24254011; 24554125; 25559189; 25764348; 26563149; 28857170; 29281059; 31334862; |
| Motif | |
| Gene Encoded By | |
| Mass | 49,678 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |