| IED ID | IndEnz0002000814 |
| Enzyme Type ID | protease000814 |
| Protein Name |
Pyrrolidone-carboxylate peptidase 1 EC 3.4.19.3 5-oxoprolyl-peptidase 1 Pyroglutamyl-peptidase I 1 PGP-I 1 Pyrase 1 |
| Gene Name | pcp1 SSO1465 |
| Organism | Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) |
| Taxonomic Lineage | cellular organisms Archaea TACK group Crenarchaeota Thermoprotei Sulfolobales Sulfolobaceae Saccharolobus Saccharolobus solfataricus (Sulfolobus solfataricus) Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) |
| Enzyme Sequence | MTVLLFGFEPFLEYKENPSQLIVEALNRSTILKEEVKGVILPVEYKKIEDVIVTKIRETKPILTLGIGLAPGRAKITPEKIAINYRYSREGDNAGKKYRGEKIDPLGQDGIFTNIPVEDLVDLLNENGIPAELSLSAGSYLCNNAMYIIIREARKYNSLGGFIHVPLHESYAARIQRSIPSMSLDTMIRGIKLSIEFILTNKNKKENLTLS |
| Enzyme Length | 211 |
| Uniprot Accession Number | P58201 |
| Absorption | |
| Active Site | ACT_SITE 79; /evidence=ECO:0000250; ACT_SITE 142; /evidence=ECO:0000250; ACT_SITE 164; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Release of an N-terminal pyroglutamyl group from a polypeptide, the second amino acid generally not being Pro.; EC=3.4.19.3; |
| DNA Binding | |
| EC Number | 3.4.19.3 |
| Enzyme Function | FUNCTION: Removes 5-oxoproline from various penultimate amino acid residues except L-proline. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1) |
| Keywords | Cytoplasm;Hydrolase;Protease;Reference proteome;Thiol protease |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 23,681 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |