| IED ID | IndEnz0002000833 |
| Enzyme Type ID | protease000833 |
| Protein Name |
Pyrrolidone-carboxylate peptidase EC 3.4.19.3 5-oxoprolyl-peptidase Pyroglutamyl-peptidase I PGP-I Pyrase |
| Gene Name | pcp BH3631 |
| Organism | Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (Bacillus halodurans) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Bacillaceae Alkalihalobacillus Alkalihalobacillus halodurans (Bacillus halodurans) Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (Bacillus halodurans) |
| Enzyme Sequence | MGNIILLTGFQPFLDYSINPTEAIVKELNGRKIGEYEVRGVILPVSFRESGDLLLHHFQTVQPTAVFMLGLAAGRGKITPERVAININSGPEDRDGIAPVDEPIRQGGPAAYFSTLPVRRLIQRLNEEGFPAEMSNSAGTYVCNHVMYRMLDYLHEKGSEQVAAGFVHLPASKELAAQHHSLPSMDLKDLTRAVTLMIEEL |
| Enzyme Length | 201 |
| Uniprot Accession Number | Q9K6U4 |
| Absorption | |
| Active Site | ACT_SITE 81; /evidence=ECO:0000250; ACT_SITE 143; /evidence=ECO:0000250; ACT_SITE 168; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Release of an N-terminal pyroglutamyl group from a polypeptide, the second amino acid generally not being Pro.; EC=3.4.19.3; |
| DNA Binding | |
| EC Number | 3.4.19.3 |
| Enzyme Function | FUNCTION: Removes 5-oxoproline from various penultimate amino acid residues except L-proline. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1) |
| Keywords | Cytoplasm;Hydrolase;Protease;Reference proteome;Thiol protease |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 22,181 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |