| IED ID | IndEnz0002000899 |
| Enzyme Type ID | protease000899 |
| Protein Name |
RNA2 polyprotein P2 Cleaved into: Movement protein; Capsid protein VP25; Capsid protein VP20; Capsid protein VP24 |
| Gene Name | |
| Organism | Cherry rasp leaf virus (isolate Potato/United States) (CRLV) |
| Taxonomic Lineage | Viruses Riboviria Orthornavirae Pisuviricota Pisoniviricetes Picornavirales Secoviridae Cheravirus Cherry rasp leaf virus (CRLV) Cherry rasp leaf virus (isolate Potato/United States) (CRLV) |
| Enzyme Sequence | MEPERSQLAPEEVPDSFRVETPAAMLARLRAESAAKKEAARRAAMPYNDDLLVGSELTYLAKDDVFGCGRSALKRLFSRPSAEENVVVSHPLSVKEQVVRYQRPRTDHDPYVAVYTPLPHITEEQARKLMEKGFSNSSNVALDMAVQSHVGQGTPLLAMCGIMDSRTDDPNEALQVAGYFDLGRDRCDLISLPLINFPLNKEDFDDYMRGLYLCTMFHNVRGFQNNKALCSYSAVGFDQHKETPRCIRSRVKESWEDILARNNENEFSRVQSGQNLLNAIEKERNEAIPDVGAHQFACVPPSKGTPQTSLLTSDGVIKRPNFTLPRSASTRFNMPLNMRYSGRNSVDTARHSLTTNSGGRSTSLRQDPNLLEGQGPSIDFTKIIFPTVVERNFSNPRAEIVNTIKQLYGDTVETLSVNPPESYSAERLIGRVFSTLHGSFGATDLVEGKVLMSVKIVDLLSSANLGALLLAEVLGGNLTMRVTALITLNKYTSFALKLVYDELAQLAPDATNFGVASVLPGAIFPSQEKSFSFDFNIFSMGSYINFKENEGFGRISLVALSSPNLPDQMPDSANITLEFSVVNVDTSVYNLGQGQCLDLDRFPVHVTSKSKALSGGAKHAQAEFSLNLYELGPHFNRFQAICGHLAGYSGDLIIDWMISASALTNGRCYIVPVYDQNTFSEVSEEKLRQCKYVSKELSLNRSGTVHMPFSSSFGSYTKNKYPKLLFVFPGGISGPSGETIHVNIQVRDVLHFSGLGHQLLKPILAAEGPDPFSFHLFYLHCGTLKTESLNKGGMWCVPVSPINLAAMKHGTGSSLVFNESFVSKTHNWLHYMASCTAYWRGTLTYELRVTYNSRVNAVANLVAFYTSQVEDLFGFSDKAVGDTGIASICGDAFSVRISIPFVTPTLWLRTYRNAYDVFTSCNGSLYFHLPTSGVKSVQLFVRAESDFSFERFRALKAEYT |
| Enzyme Length | 960 |
| Uniprot Accession Number | Q6EWG8 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: [Movement protein]: Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier. Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity). {ECO:0000250}.; FUNCTION: Capsid proteins VP20, VP24, and VP25 form a capsid enclosing the viral positive strand RNA genome. Together they form an icosahedral capsid pseudo T=3 with a diameter of approximately 30 nm (Potential). {ECO:0000305}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (4); Region (1); Site (3) |
| Keywords | Capsid protein;Host cell junction;Reference proteome;Transport;Viral movement protein;Virion |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: [Movement protein]: Host cell junction, host plasmodesma {ECO:0000250}.; SUBCELLULAR LOCATION: [Capsid protein VP25]: Virion {ECO:0000305}.; SUBCELLULAR LOCATION: [Capsid protein VP20]: Virion {ECO:0000305}.; SUBCELLULAR LOCATION: [Capsid protein VP24]: Virion {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | PTM: Specific enzymatic cleavages in vivo by the P1 encoded 3C-like protease yield mature proteins. {ECO:0000250}. |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 106,236 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |