Detail Information for IndEnz0002000910
IED ID IndEnz0002000910
Enzyme Type ID protease000910
Protein Name RNA2 polyprotein
Cleaved into: Movement protein; Capsid protein VP35; Capsid protein VP26; Capsid protein VP23
Gene Name
Organism Tomato torrado virus (isolate Solanum lycopersicum/Spain/PRIToTV0301/-) (ToTV)
Taxonomic Lineage Viruses Riboviria Orthornavirae Pisuviricota Pisoniviricetes Picornavirales Secoviridae Torradovirus Tomato torrado virus Tomato torrado virus (isolate Solanum lycopersicum/Spain/PRIToTV0301/-) (ToTV)
Enzyme Sequence MMMSSVAGQRKGPSDKSAAVSEQLIAQITAAVEAGNKNLLRKLGMGSYGILYGAQEKKAMELFDPEDVHNITSLWSSFKKTFTSSRDHGNLFFHLYGVMFFMVPHVHGGEGSVKISLCSSNDPTNPVLQEKVLYFSGGAQAVLMSPTITLPFVKRGPMFYYTMECLGTRAQIPCSVVAIWKQKIDIRSAIYSKQETMSWAIEALHRPQFFQDRQEAAQYISSVYSNATSSATDSVLPFVGAQLGDTKMNVPSEARMIRSSSLRVPMLKVQSKRFSSMEIPSTSTAHLLGTTRDETVIQEESRYEEEGDDGVLFPVKKAQGLNYSHVWDNLGIESFVDVELPENWDELSVRQQVAAAMIAFANKGVCLVPKHIINRDKHNIHLENITEHNYLVILERYGIVNAGSLARTENWYNLTLAQRVEELIYQRDDAYFMFGDNTNPYPPFDCYDGLTLKVRSELERVAKEQARQRFYKEAARAQVKNKVAQTSVEEIPSTSFATKVAMESGSVDSMKIAIQAEAANEAVRPNEVMFEFGQEMNNEGATELELQQPACVASNSFFNVGVFEFAWKKSSSVAAEVLSLALPAALFGKSKEMSMGSQMLRYYDAALIMYKVILYISGMGAISGQLALVWDECNVLNRKKEFINIASLYASKHRLVSASEQSSGEFCFTPTGIGKFVPLDPASGAYDLGSIRVFVTHPLASATELESIPCHIHLQCKVLSTNIMQPPRLRAQAQFGMKPDQTHFPRFPTNQVLLHYNWGVAASMGTTLVSIFSPSGIYESDGTLQPSLLGNIARNCKWWTGTCVFEICIEKTQFHSGSLAIGLGTLNTSMSTPHDILNMPHVICNLEMGRKFYFRCTITNWNGKNLLTTGRKSSLPRPKHMSHMRLFATVLKPLVSTSIHLDTVGVTVQLKCIEDLVLGGTVSVKPIYGHWTKGKNAVDFLFSEMDLSQRKEIEKLRKENVETFDEKGKKQPQVQVPLRDKFSYGAVQYFVMNWKDEERLLVLPCAPWSVRFPQGALVQEAITCPFIDWCSSFCYWSGSLEYTIIVHRVQTSNNIGGVLNITLDSSGYPFPLGISKGTYVVSAGGGAKWAFTYGMSDNIFSFVVHDDEFFPRRHTKARAIDPNASRIMTLQDRLGNLIINLPAKDVISSLEILVKPGPDFKLQLAQAPSANHEKHLGDMQTHTYLYTPDFSELRSFEN
Enzyme Length 1198
Uniprot Accession Number A1XIQ1
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: [Movement protein]: Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier. Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity). {ECO:0000250}.; FUNCTION: Capsid proteins VP35, VP26, and VP23 form a capsid enclosing the viral positive strand RNA genome. Together they form an icosahedral capsid pseudo T=3 with a diameter of approximately 30 nm (Potential). {ECO:0000305}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (4)
Keywords Capsid protein;Host cell junction;Reference proteome;Transport;Viral movement protein;Virion
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: [Movement protein]: Host cell junction. Host cell junction, host plasmodesma.; SUBCELLULAR LOCATION: [Capsid protein VP35]: Virion {ECO:0000305}.; SUBCELLULAR LOCATION: [Capsid protein VP26]: Virion {ECO:0000305}.; SUBCELLULAR LOCATION: [Capsid protein VP23]: Virion {ECO:0000305}.
Modified Residue
Post Translational Modification PTM: Specific enzymatic cleavages in vivo by the P1 encoded 3C-like protease yield mature proteins. {ECO:0000250}.
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 133,709
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda