| IED ID |
IndEnz0002000927 |
| Enzyme Type ID |
protease000927 |
| Protein Name |
Peptidase inhibitor 15-A
|
| Gene Name |
pi15a pi15 si:rp71-1m12.1 |
| Organism |
Danio rerio (Zebrafish) (Brachydanio rerio) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Deuterostomia
Chordata
Craniata
Vertebrata
Gnathostomata (jawed vertebrates)
Teleostomi
Euteleostomi
Actinopterygii
Actinopteri
Neopterygii
Teleostei
Osteoglossocephalai
Clupeocephala
Otomorpha
Ostariophysi
Otophysi
Cypriniphysae
Cypriniformes (carps and others)
Cyprinoidei
Danionidae
Danioninae
Danio
Danio rerio (Zebrafish) (Brachydanio rerio)
|
| Enzyme Sequence |
MNENRLAIDILLLCISCGASALAGFSPTASSSLPATNLTDIGFAPPKYLTEAANIPKTRRKRYISQNDMLAILDYHNKVRGKVFPPASNMEYMVWDDTLAKTAEQWASTCIWEHGPRNLLRFLGQNLSVRTGRYRSILQLVKPWHDEVKDYSFPYPRDCNPRCPLKCYGPMCTHYTQMVWATSNKVGCAINTCHNMNVWGSVWKRATYLVCNYSPKGNWIGEAPYKVGVPCSMCPPSYGGSCSNNMCFPAVNSNYLHWFK |
| Enzyme Length |
260 |
| Uniprot Accession Number |
Q7T141 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Serine protease inhibitor which displays weak inhibitory activity against trypsin (By similarity). May play a role in facial patterning during embryonic development (By similarity). {ECO:0000250|UniProtKB:O43692, ECO:0000250|UniProtKB:Q98ST6}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Domain (1); Erroneous gene model prediction (1); Glycosylation (2); Propeptide (1); Signal peptide (1) |
| Keywords |
Developmental protein;Glycoprotein;Protease inhibitor;Reference proteome;Secreted;Signal |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:O43692}. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
SIGNAL 1..21; /evidence=ECO:0000255 |
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
29,345 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|