| IED ID |
IndEnz0002000932 |
| Enzyme Type ID |
protease000932 |
| Protein Name |
Peptidase inhibitor 15
|
| Gene Name |
pi15 |
| Organism |
Xenopus laevis (African clawed frog) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Deuterostomia
Chordata
Craniata
Vertebrata
Gnathostomata (jawed vertebrates)
Teleostomi
Euteleostomi
Sarcopterygii
Dipnotetrapodomorpha
Tetrapoda
Amphibia
Batrachia
Anura
Pipoidea
Pipidae
Xenopodinae
Xenopus
Xenopus
Xenopus laevis (African clawed frog)
|
| Enzyme Sequence |
MIEMISISAAFLLSLLCETCGLVLPKSSDLAIAASNYTIIKPDLSARLDPVKAPKARRKRYISQNDMIEIVEYHNQVRGKVFPPAANMEYMVWDDNLAKLAEAWAATCIWDHGPSYLLKFLGQNLSVRTGRYKSILQLVKPWYDEVKDYAFPYPQECNPRCPLRCYGPMCTHYTQMVWATTNRIGCAIHTCHNINVWGAVWRRAVYLVCNYSPKGNWIGEAPYTIGVPCSACPPSYGGSCSDNQCFPGITSNYLHWFK |
| Enzyme Length |
258 |
| Uniprot Accession Number |
Q3KPV7 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Serine protease inhibitor which displays weak inhibitory activity against trypsin (By similarity). May be involved in facial patterning during embryonic development (By similarity). {ECO:0000250|UniProtKB:O43692, ECO:0000250|UniProtKB:Q98ST6}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Domain (1); Glycosylation (2); Propeptide (1); Signal peptide (1) |
| Keywords |
Developmental protein;Glycoprotein;Protease inhibitor;Secreted;Signal |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:O43692}. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
SIGNAL 1..21; /evidence=ECO:0000255 |
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
29,195 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|