| IED ID | IndEnz0002000962 |
| Enzyme Type ID | protease000962 |
| Protein Name |
Foldase protein PrsA EC 5.2.1.8 Protease maturation protein PrtM |
| Gene Name | prsA prtM |
| Organism | Lactococcus lactis subsp. cremoris (Streptococcus cremoris) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Lactobacillales Streptococcaceae Lactococcus (lactic streptococci) Lactococcus lactis subsp. cremoris (Streptococcus cremoris) |
| Enzyme Sequence | MKKKMRLKVLLASTATALLLLSGCQSNQTDQTVATYSGGKVTESSLYKELKQSPTTKTMLANMLIYRALNHAYGKSVSTKTVNDAYDSYKQQYGENFDAFLSQNGFSRSSFKESLRTNFLSEVALKKLKKVSESQLKAAWKTYQPKVTVQHILTSDEDTAKQVISDLAAGKDFAMLAKTDSIDTATKDNGGKISFELNNKTLDATFKDAAYKLKNGDYTQTPVKVTDGYEVIKMINHPAKGTFTSSKKALTASVYAKWSRDSSIMQRVISQVLKNQHVTIKDKDLADALDSYKKLATTN |
| Enzyme Length | 299 |
| Uniprot Accession Number | P0C2B5 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833, ChEBI:CHEBI:83834; EC=5.2.1.8; |
| DNA Binding | |
| EC Number | 5.2.1.8 |
| Enzyme Function | FUNCTION: This protein is essential for production of active forms of the serine proteinase located in or secreted from the cell envelope. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Domain (1); Lipidation (2); Mutagenesis (1); Sequence conflict (6); Signal peptide (1) |
| Keywords | Cell membrane;Isomerase;Lipoprotein;Membrane;Palmitate;Plasmid;Rotamase;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:1906066}; Lipid-anchor {ECO:0000305|PubMed:1906066}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..23; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | Plasmid pLP763; Plasmid pWV05; Plasmid pHP003 |
| Mass | 33,133 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | RHEA:16237 |
| Cross Reference Brenda |