Detail Information for IndEnz0002001037
IED ID IndEnz0002001037
Enzyme Type ID protease001037
Protein Name Serine protease inhibitor A3A
Serpin A3A
Gene Name Serpina3a
Organism Mus musculus (Mouse)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Myomorpha (mice and others) Muroidea Muridae Murinae Mus Mus Mus musculus (Mouse)
Enzyme Sequence MAFIAALGLLMVGICPAVTYWATADGQLGGHTAVQKDRDHEIQLDSVTLASINTDFAFSLYKKLALENPHKNIVFSPLSISAALALMSLGAKGNTLEEILEGLKFNLPETPEADIHQNFGHLLQMLIQPENQVQINAGNALFIDKHLQILTEFKEKARALYKAEAFTTDFQRPREATKLINDYVRKQTQGKIKELVSDLHRNTSMALVNFLNFQGFWNVTFDPEDTFLGNFTLDRKRTVNVPMMKTEELTTNYFRDEEMQSTVMELNYIGNASFLFILPDQGRIQHVEDSLQPQSLRKWRKSLRPRMLDELSLPKFSLSQDYNLNDILPELGIKEVFSTQADLSGITGAKNIRVSQMIHQAALDVTETHTEADVITIARYNFQSAKIKAKIVKVDREFLYLILDPMFKSISVMGKVINPLTN
Enzyme Length 422
Uniprot Accession Number Q6P4P1
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Alternative sequence (2); Chain (1); Glycosylation (3); Region (1); Sequence conflict (1); Signal peptide (1); Site (1)
Keywords Alternative splicing;Glycoprotein;Protease inhibitor;Reference proteome;Secreted;Serine protease inhibitor;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..17; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 11217851; 12466851; 21267068; 21677750; 32274496;
Motif
Gene Encoded By
Mass 47,772
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda