| IED ID | IndEnz0002001070 |
| Enzyme Type ID | protease001070 |
| Protein Name |
Vitellogenic carboxypeptidase EC 3.4.16.- |
| Gene Name | VCP AAEL006563 |
| Organism | Aedes aegypti (Yellowfever mosquito) (Culex aegypti) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Endopterygota Diptera Nematocera Culicomorpha Culicoidea Culicidae (mosquitos) Culicinae Aedini Aedes Stegomyia Aedes aegypti (Yellowfever mosquito) (Culex aegypti) |
| Enzyme Sequence | MVKFHLLVLIAFTCYTCSDATLWNPYKKLMRGSASPRRPGESGEPLFLTPLLQDGKIEEARNKARVNHPMLSSVESYSGFMTVDAKHNSNLFFWYVPAKNNREQAPILVWLQGGPGASSLFGMFEENGPFHIHRNKSVKQREYSWHQNHHMIYIDNPVGTGFSFTDSDEGYSTNEEHVGENLMKFIQQFFVLFPNLLKHPFYISGESYGGKFVPAFGYAIHNSQSQPKINLQGLAIGDGYTDPLNQLNYGEYLYELGLIDLNGRKKFDEDTAAAIACAERKDMKCANRLIQGLFDGLDGQESYFKKVTGFSSYYNFIKGDEESKQDSVLMEFLSNPEVRKGIHVGELPFHDSDGHNKVAEMLSEDTLDTVAPWVSKLLSHYRVLFYNGQLDIICAYPMTVDFLMKMPFDGDSEYKRANREIYRVDGEIAGYKKRAGRLQEVLIRNAGHMVPRDQPKWAFDMITSFTHKNYL |
| Enzyme Length | 471 |
| Uniprot Accession Number | P42660 |
| Absorption | |
| Active Site | ACT_SITE 207; /evidence=ECO:0000250; ACT_SITE 391; /evidence=ECO:0000250; ACT_SITE 448; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.16.- |
| Enzyme Function | FUNCTION: May play a role in activating hydrolytic enzymes that are involved in the degradation of yolk proteins in developing embryos or may function as an exopeptidase in the degradation of vitellogenin. {ECO:0000269|PubMed:1961751}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Frameshift (1); Glycosylation (1); Sequence conflict (3); Signal peptide (1) |
| Keywords | Carboxypeptidase;Direct protein sequencing;Glycoprotein;Hydrolase;Protease;Reference proteome;Secreted;Signal |
| Interact With | |
| Induction | INDUCTION: By 20-hydroxyecdysone. {ECO:0000269|PubMed:1961751}. |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:1961751}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..19; /evidence=ECO:0000269|PubMed:1961751 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 53,766 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |