Detail Information for IndEnz0002001071
IED ID IndEnz0002001071
Enzyme Type ID protease001071
Protein Name Venom serine carboxypeptidase
EC 3.4.16.5
allergen Api m 9
Gene Name
Organism Apis mellifera (Honeybee)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Endopterygota Hymenoptera Apocrita (wasps ants and bees) Aculeata Apoidea (bees) Apidae (bumble bees and honey bees) Apinae (honey bees) Apini Apis Apis mellifera (Honeybee)
Enzyme Sequence MKKLVLLQFLFFISFARGFTNVYPKPKYCPLLHEEDAGIPLFLTPLIENGKIDEARNKAVIQHKEVEAISSYAGFLTVNKKYNSNMFFWFFPALHDPKTAPVVLWLQGGPGATSMYGLFLENGPFIVTKNKTLKMREYSWNKCHNLLYIDNPVGTGFSFTEDERGYATNETHVGRDVHTALVQFFELFPELQTNDFYVTGESYGGKYVPAVSHAIKDYNIKAKIKINLKGLAIGNGLTDPVNQLDYGDYLYQLGLLDANGRNLFQKYEEQGKNLIKQEKWLEAFDLFDELLDGDITQQPSLYKNLTGFDYYFNYLHEKDPSNDSDYMVEWLQRADVRKAIHVGNRTFIPESKKVEKYMKADVMQSLAVLIADLTQHYRVLIYNGQLDIIVAYPLTENYLQKLKWPGAEKYKTAQRKVWFVGNELAGYSKTVDSLTEVLVRNAGHMVPLDQPKWALDLITRFTHNKGF
Enzyme Length 467
Uniprot Accession Number C9WMM5
Absorption
Active Site ACT_SITE 202; /evidence=ECO:0000250; ACT_SITE 387; /evidence=ECO:0000250; ACT_SITE 444; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Release of a C-terminal amino acid with broad specificity.; EC=3.4.16.5; Evidence={ECO:0000255|PROSITE-ProRule:PRU10074, ECO:0000255|PROSITE-ProRule:PRU10075};
DNA Binding
EC Number 3.4.16.5
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Chain (1); Glycosylation (5); Signal peptide (1)
Keywords Allergen;Carboxypeptidase;Glycoprotein;Hydrolase;Protease;Reference proteome;Secreted;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..18; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 53,702
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda