| IED ID |
IndEnz0002001098 |
| Enzyme Type ID |
protease001098 |
| Protein Name |
Variegin
|
| Gene Name |
|
| Organism |
Amblyomma variegatum (Tropical bont tick) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Protostomia
Ecdysozoa
Panarthropoda
Arthropoda
Chelicerata
Arachnida
Acari
Parasitiformes
Ixodida (ticks)
Ixodoidea
Ixodidae (hardbacked ticks)
Amblyomminae
Amblyomma
Amblyomma variegatum (Tropical bont tick)
|
| Enzyme Sequence |
SDQGDVAEPKMHKTAPPFDFEAIPEEYLDDES |
| Enzyme Length |
32 |
| Uniprot Accession Number |
P85800 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Thrombin inhibitor. Does not inhibit other serine proteases. {ECO:0000269|PubMed:17684009}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Compositional bias (1); Glycosylation (1); Natural variant (1); Peptide (1); Region (2) |
| Keywords |
3D-structure;Direct protein sequencing;Glycoprotein;Protease inhibitor;Secreted;Serine protease inhibitor |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17684009}. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
X-ray crystallography (1) |
| Cross Reference PDB |
3B23;
|
| Mapped Pubmed ID |
22053189;
|
| Motif |
|
| Gene Encoded By |
|
| Mass |
3,609 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|