| IED ID | IndEnz0002001145 |
| Enzyme Type ID | protease001145 |
| Protein Name |
Calpain-like protease palB/RIM13 EC 3.4.22.- Cysteine protease RIM13 |
| Gene Name | RIM13 CAALFM_C505030CA CaO19.11478 CaO19.3995 |
| Organism | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Debaryomycetaceae Candida/Lodderomyces clade Candida Candida albicans (Yeast) Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
| Enzyme Sequence | MPTPCLEQFLHHLEKSHLYLSIDNTKQAKKECLESIKILNSIAKTTPLPEIKVLSQYTLNHYESLDKPRTISDKLEWISSKLTQETFFPPVIQFNENFTSHNELFVDTISPIQDNDNKIFEKLPNKLAKFEYIEISNWDNDITHLKNLYQDILPNCSFVSSFLAIIDANIPIIDTITPQKSSQKYKVSLRFNGALRNVIVDSKFPIMPNSRNLIIKSYSDTELYWPALIEKAYLTIMGNGYNFSGSNMANDAYVLSGWLPQIIKLSNGQLPSNIDDLWRLRTQGKVTMGIGTGTLSKQLSSQLHLVSGHDYVIDNIKDGVITVKNPWLDPKDRVVEIKNFNHFKYLYVNWKPDHKPYQHYFLYQAKPNTYNQPQFTIKCMEETWILLERHLSETSSSPSPHWMDMNVFETEYKIITPSQYKKYLSVETNNRLQLIKLKPGVFTIVISSNKPCRFTLSSFNAMFSKSKYKYDYTETVNGEWNSDINGGNWAMSTYINNPQYDIIAKQTTELIMGMHGQGQINFHLFHSSSDSMGERIQNFDKTKLINYQNYNASYQSSSYRLTPGHYKLVVSEYYRSIGTYQLVLNSSEPITITKIPPFLGLYNISKSFNWDNTNRFKLKFETTGYNSKVKIKIAYFNGESDFELQTSYRPAMRASLFNSQTKQPIQINEQFNDSLYGVFLHEILPSPEEYILLIERFEIGYGRCVVEIGCNNKVILK |
| Enzyme Length | 717 |
| Uniprot Accession Number | Q5AK25 |
| Absorption | |
| Active Site | ACT_SITE 156; /evidence=ECO:0000255|PROSITE-ProRule:PRU00239; ACT_SITE 309; /evidence=ECO:0000255|PROSITE-ProRule:PRU00239; ACT_SITE 325; /evidence=ECO:0000255|PROSITE-ProRule:PRU00239 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | FUNCTION: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH. {ECO:0000250, ECO:0000269|PubMed:15189995}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Domain (1) |
| Keywords | Hydrolase;Protease;Reference proteome;Thiol protease |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 83,070 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |