Detail Information for IndEnz0002001148
IED ID IndEnz0002001148
Enzyme Type ID protease001148
Protein Name pH-response regulator protein palA/RIM20
Gene Name RIM20 CNBG4510
Organism Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Basidiomycota Agaricomycotina Tremellomycetes Tremellales (jelly fungi) Cryptococcaceae Cryptococcus Cryptococcus neoformans species complex Cryptococcus neoformans (Filobasidiella neoformans) Cryptococcus neoformans var. neoformans Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans)
Enzyme Sequence MSNFLPIPTKAATPLPSFAKHLLDYISAHFRDTHSEAFRKDVDVLVGMRKDWVEAKLEAHPEIIRAFMRYHAQLAFLSTKFPSDINLPFAYYLPFPATFSLSPDAPISLSSLTFERACVLFNMTALYASMAAAERRAEAEGIKRALGYLTAAAGVLEYLITSVLPTLRSELSSPQAAGYDMTESFLGTLKEFVLAEAQECYWQQAVLQGTYKNGLIGKLSMKVSEYYKAALASMNGTDYPSSSYFPLNWTAHMNVKQMHFEAAAQFRLSQEDLEKSRYGEEIGRLKVAESLAKKGLDAARKGVADSVVSDLKQLHAAIKSSLERAVRDNDLVYVQPIPPANQLAPIVGVGMVKVNVPAEVAEPVAWLMGGKAGMEPLFSGLVPYGVHLALSIYDDRKDTLVRDLDGKREELDGLAASTLQSLNLPGSIQALDRPVGLPPSLLKKSEEVASSGGIERIRSLLDEVNRLAHANVQSLNEAMDILDQEATENESLIARQPELQQTRQPSHVANQPLIQMAEQYEATIKQAGGSDATVRAKWEEWARLVGILAAGEMEMEDYVPGTTSPSGSLPPSVRPLRASLEELDDRIAHRARLVREARQISAADDIRPEVLKEAAKLAHGGSGDVKTEWFEDLFEKGLEKYMGVKREMDEEVAKHDELLEQIRTQNESFLSERKDDPIIKERERRLQDMDLAYWKWREIVDNAEEGIKFYNSFAEMLHGFKAACGQFLNTRRIDVGQMTTQFQQQMNVSEPQQQPEPRYQSPSPQSFQPSFSPSPSHFQPSAPSSFSSSPVRSPAPSAPARRESPPKTLSFLPHPSSSAWQPASVDFLPPPPPPPILRSGGIQSQPKVAPPVTPSITAIRDQTQGTPRRMTRAAAAAAERDEATERNKYSSGGPRRKGGGVV
Enzyme Length 902
Uniprot Accession Number P0CM47
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH. May act as a scaffold protein that recruits the calpain-like protease RIM13 via VPS32 to its substrate RIM101 (By similarity). {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Compositional bias (4); Domain (1); Erroneous gene model prediction (1); Region (1)
Keywords
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 99,638
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda