| IED ID | IndEnz0002001149 |
| Enzyme Type ID | protease001149 |
| Protein Name |
Calpain-like protease palB/RIM13 EC 3.4.22.- Cysteine protease RIM13 |
| Gene Name | RIM13 CNH02440 |
| Organism | Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Basidiomycota Agaricomycotina Tremellomycetes Tremellales (jelly fungi) Cryptococcaceae Cryptococcus Cryptococcus neoformans species complex Cryptococcus neoformans (Filobasidiella neoformans) Cryptococcus neoformans var. neoformans Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) |
| Enzyme Sequence | MPFCSYQEGLKVASDLGNKAIQTEASLSSLSPVASPIPTLQKAFPIYISAAEAYGHLLSSKLVPQSDIETVKRKWRLVLERAEKVKSRIEQLGGHVAKAEIGDRGEEIAVLRRASLINGVAVELWRPPGDTFDAGEPYREAVQPELAAAQLDMDPEWRDIQADCWLHQAPNEGDWVMRQGPVSDCSVVAAMGVGIKHAGQFGTAFGWENLYPQDAHGRPRRSKNGKHILKLLLNGAWRSVVLDSLLPFSKRDKTPLFTTCHPAPHILPTSVGSPWAPLALKGYFKVHGGYSLRGSNPSSDIYEFMGWIPERIGLKEGFQREKEWKRMKEAWHKGNVMVSLGTGSKVSEGLVKLHAYGVIRLREEGHERILDIFDPGATSFTMSWDQVCAEFEALHLNWKPSVMPNTATRHWSWPKPPDLPSDADPGMMNTRYRLHVNASSPSSSLSEVWILLSQHITSRDRPLDDIALHVFEGLGPNNSRNLGAIYSEGLERTNPYTNSNHLLVRYQLRRPTSDLTLIPSRDRGIDQTGFTLNAFAPASISLSLERISRTLPFTQRISGNLTDRSAGGHPGWPTHMTNPQYKVVVRPGEGKSEISGRIILHGEKDVPWNVKLIWGRGQLVYELSEDLIVADTGSYSYGIAYCDIPELQPDTYTLIVSAFEPGQTGLFSLSLEATAPVSIIPIAAEGAGMYNRVVNGFWTERTAGGRPSGGTYESNPRVEMVLSKPATIQSRLYLPTRSPVPINLTIFKRAQGGALGEQLVTTGPYSDSICGVSTGKMKLDSGVYLLVPSSYEKSKGGWVLKIWSDVALSAEIVG |
| Enzyme Length | 814 |
| Uniprot Accession Number | P0CQ06 |
| Absorption | |
| Active Site | ACT_SITE 185; /evidence=ECO:0000255|PROSITE-ProRule:PRU00239; ACT_SITE 354; /evidence=ECO:0000255|PROSITE-ProRule:PRU00239 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | FUNCTION: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Domain (1); Erroneous gene model prediction (1) |
| Keywords | Hydrolase;Protease;Reference proteome;Thiol protease |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 89,673 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |