| IED ID | IndEnz0002001251 |
| Enzyme Type ID | protease001251 |
| Protein Name |
Rhomboid-like protein 15 AtRBL15 EC 3.4.21.- |
| Gene Name | RBL15 RBL11 At3g58460 F14P22.50 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MRPNIVTEAGVQTRVGQWWNAIPFLTSSVVVVCGVIYLICLLTGYDTFYEVCFLPSAIISRFQVYRFYTAIIFHGSLLHVLFNMMALVPMGSELERIMGSVRLLYLTVLLATTNAVLHLLIASLAGYNPFYQYDHLMNECAIGFSGILFSMIVIETSLSGVTSRSVFGLFNVPAKLYPWILLIVFQLLMTNVSLLGHLCGILSGFSYSYGLFNFLMPGSSFFTTIESASWMSSFIRRPKFIMCTGGNPSSYIPTYSAQNTTSSGFSTGNAWRSLSSWLPQREASNQSSEDSRFPGRGRTLSTARDPTAPAGETDPNLHARLLEDSSSPDRLSDATVNTVADSRQAPIANAAVLPQSQGRVAASEEQIQKLVAMGFDRTQVEVALAAADDDLTVAVEILMSQQA |
| Enzyme Length | 403 |
| Uniprot Accession Number | Q8LB17 |
| Absorption | |
| Active Site | ACT_SITE 145; /note=Nucleophile; /evidence=ECO:0000250|UniProtKB:P54493; ACT_SITE 197; /note=Charge relay system; /evidence=ECO:0000250|UniProtKB:P54493 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.21.- |
| Enzyme Function | FUNCTION: Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis. May function in senescence. {ECO:0000303|PubMed:22007993}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Alternative sequence (2); Beta strand (1); Chain (1); Domain (1); Erroneous gene model prediction (1); Helix (3); Region (1); Sequence conflict (1); Transmembrane (6); Turn (1) |
| Keywords | 3D-structure;Alternative splicing;Hydrolase;Membrane;Protease;Reference proteome;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | NMR spectroscopy (1) |
| Cross Reference PDB | 1VG5; |
| Mapped Pubmed ID | 21798944; |
| Motif | |
| Gene Encoded By | |
| Mass | 44,145 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |