Detail Information for IndEnz0002001283
IED ID IndEnz0002001283
Enzyme Type ID protease001283
Protein Name Metacaspase-1B
EC 3.4.22.-
Gene Name casB NCU02400
Organism Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Sordariomycetes Sordariomycetidae Sordariales Sordariaceae Neurospora Neurospora crassa Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Enzyme Sequence MSGYPGAGYNGGGYVPPPQPQYGGYYPPQPAYNAYQQPPPQQQQYMVYHQPSPGPQQHQHWNPQQQTPAPQGYGNPPNSHYGRPEANMPTVNSNSYAHGNHQAPPPPPQAPQQFGYGAPADYAFRYSQCNGRHKALLIGINYFGQRGQLRGCINDVRNMSSYLVEHFRYKREDMVILTDDQQNPMSQPTKQNILRAMHWLVKDARPNDSLFFHYSGHGGQTKDLDGDEEDGYDEVIYPVDFRQVGHITDDEMHRIMVRPLQAGVRLTAIFDSCHSGTALDLPYIYSTQGILKEPNLAKEAGQGLLGAISSYSQGDLYGVANNIMGIFKKATGGNDAHARTLATKTSPADVVMFSGSKDDQTSADATIASQATGAMSWAFINALKKNPQQSYVQLLNSIRDELQMRYTQKPQLSCSHPLDTNLLFVM
Enzyme Length 426
Uniprot Accession Number Q7S4N5
Absorption
Active Site ACT_SITE 217; /evidence=ECO:0000250; ACT_SITE 273; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.22.-
Enzyme Function FUNCTION: Involved in cell death (apoptosis). {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Compositional bias (2); Propeptide (1); Region (1)
Keywords Apoptosis;Hydrolase;Protease;Reference proteome;Thiol protease;Zymogen
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 47,287
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda