Detail Information for IndEnz0002001284
IED ID IndEnz0002001284
Enzyme Type ID protease001284
Protein Name Metacaspase-1
EC 3.4.22.-
Gene Name MCA1 LELG_02861
Organism Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Debaryomycetaceae Candida/Lodderomyces clade Lodderomyces Lodderomyces elongisporus Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)
Enzyme Sequence MFPGQGRHTYGGQQQLLQLQQYNYGPPQGPPPNGYGPPPGPPPNGYGPPPGPPPQNSWGYGNPSGTQSSNQQRYQGQQSGQQNYNGGYQRPSQPPPQQSGNQRGQPGQNGEPDYGHQYGSGQYSRPPTNQQSFGVENYNYQYSACNGRKKALLVGINYIGTANELRGPINDVNNVEQFLLTHGFKSDDIVKLTDDQRVQRAIPTRQNILDAIQWLVKDARPNDSLFFHYSGHGGQTEDQPDQYGNYDEDDGYDEVIYPLDFQTNGFIVDDLLHDMMVKTLPPGCRMTALFDSCHSGSVLDLPYMYSTKGVLKEPNVMKEAGQGLLQAAMSYATGNSAGIFKGLSSSVKSFMNQGRSSQANEYSKQTKTAACDAISLSGCKDDQTSADSSIGGQATGAMSYAFLTVMNQNPNQSYLSLLQNMRTILQSKYSQKPQLTASHPIDCNLQFIF
Enzyme Length 449
Uniprot Accession Number A5DZS4
Absorption
Active Site ACT_SITE 232; /evidence=ECO:0000250; ACT_SITE 293; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.22.-
Enzyme Function FUNCTION: Involved in cell death (apoptosis). {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Compositional bias (3); Propeptide (1); Region (1)
Keywords Apoptosis;Hydrolase;Protease;Reference proteome;Thiol protease;Zymogen
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 49,227
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda