Detail Information for IndEnz0002001289
IED ID IndEnz0002001289
Enzyme Type ID protease001289
Protein Name Extracellular metalloproteinase mep
EC 3.4.24.-
Elastinolytic metalloproteinase mep
Fungalysin mep
Gene Name mep GLRG_06543
Organism Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize anthracnose fungus) (Glomerella graminicola)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Sordariomycetes Hypocreomycetidae Glomerellales Glomerellaceae Colletotrichum Colletotrichum graminicola species complex Colletotrichum graminicola (Maize anthracnose fungus) (Glomerella graminicola) Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize anthracnose fungus) (Glomerella graminicola)
Enzyme Sequence MYRSMKSLALLGLLGPTSQVFAHPATGHAHNIGRRGVDIEAFRLPQVGSYTNATEIETTPPIALLKRESYVETATELVKKLAPNSEFRLVGDHYVGTNGIGHVNFKQTVHGLDIDNGDFNVNIGKDGKVFSYGNNFFKGEAPEASPLKKRDFKDPVSALKGAKDVLQLPVEAASASAEPKEGTEVYSIKGTSGTVSDPEARLVYFVKADGSLALSWRVETDITENWLLTYVDAETGTDVHGVVDYVSDLANYRVYPWGVNDPTEGDRVLVTDPWDISASPLTWQSDGTTNYTTTRGNNGIAQSNPSGGTAYLNNYRPTSAARNFDYQYTTSLTTPSSYIDASIAQLYYTANHYHDLLYTLGFTESAGNFQINNNGKGGVGNDFVVLFAQDGSGTNNANFLTPPDGSNGRMRMYLWTMSTPRRDCSFEAGVVIHEYTHGLSTRLTGGPANSNCLNALESGGMGEGWGDFFATAIRLKPTDTRATDYSMGAWVYNNPAGIRSVLYSTSMTTTPNTYSTINGVSSVHRIGETWATTLYEVLWNLIDKHGKNDGPRPEFDSNGVPTDGKYLTLKLVLDGMALQPCSPNFIQARDAILDADKALTGGDNLCELWTAFAKRGLGSNAVYSSSNRRDGFNVPAGVC
Enzyme Length 639
Uniprot Accession Number E3QKL1
Absorption
Active Site ACT_SITE 434; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.24.-
Enzyme Function FUNCTION: Secreted metalloproteinase that allows assimilation of proteinaceous substrates. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Glycosylation (2); Metal binding (2); Propeptide (1); Signal peptide (1)
Keywords Glycoprotein;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Secreted;Signal;Zinc;Zymogen
Interact With
Induction INDUCTION: Expression is controlled by the prtT transcription factor.
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..22; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 69,318
Kinetics
Metal Binding METAL 433; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 437; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095
Rhea ID
Cross Reference Brenda