| IED ID | IndEnz0002001354 |
| Enzyme Type ID | protease001354 |
| Protein Name |
Tubulointerstitial nephritis antigen TIN-Ag |
| Gene Name | TINAG |
| Organism | Bos taurus (Bovine) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Laurasiatheria Artiodactyla Ruminantia Pecora Bovidae Bovinae Bos (oxen cattle) Bos taurus (Bovine) |
| Enzyme Sequence | MCAGYKILILAYLTTEIWMERQYLSQREVDPGAEFTRNHTISEGTRFKRAVFEGQYCRRFGCCADRDDGCVTQFYEADALCYCDKFCERENSDCCPDYKSFCREEKGWPPRTKPWSPEGCHRDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVCLVQPGLIEHVNKGDYGWTAQNYSQFWGMTLEEGFKYRLGTLPPSPLLLSMNEVTASLTKTTDLPEFFIASYKWPGWTHGPLDQKNCAASWAFSTASVAADRIAIQSQGRYTANLSPQNLISCCAKKRHGCNSGSVDRAWWYLRKRGLVSHACYPLFKDQNATNNGCAMASRSDGRGKRHATTPCPNSIEKSNRIYQCSPPYRVSSNETEIMREIMQNGPVQAIMQVHEDFFNYKTGIYRHITSTNEDSEKYRKFRTHAVKLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVNESDIEKLIIAAWGQLTSADEP |
| Enzyme Length | 476 |
| Uniprot Accession Number | Q3SZI1 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Mediates adhesion of proximal tubule epithelial cells via integrins alpha3-beta1 and alphaV-beta3. This is a non catalytic peptidase C1 family protein (By similarity). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Disulfide bond (2); Domain (1); Glycosylation (5); Site (1) |
| Keywords | Basement membrane;Cell adhesion;Disulfide bond;Extracellular matrix;Glycoprotein;Reference proteome;Secreted |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 54,235 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |