Detail Information for IndEnz0002001374
IED ID IndEnz0002001374
Enzyme Type ID protease001374
Protein Name Probable thylakoidal processing peptidase 2, chloroplastic
EC 3.4.21.89
Signal peptidase I-2
Gene Name TPP2 At1g06870 F4H5.6
Organism Arabidopsis thaliana (Mouse-ear cress)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress)
Enzyme Sequence MAIRVTFTYSSYVARSIASSAGTRVGTGDVRSCFETWVRPRFCGHNQIPDIVDKSPGSNTWGPSSGPRARPASSMYSTIAREILEEGCKSPLVLGMISLMNLTGAPQFSGMTGLGISPFKTSSVIPFLRGSKWMPCSIPATLSTDIAEVDRGGKVCDPKVKLELSDKVSNGGNGWVNKLLNICSEDAKAAFTAVTVSLLFRSALAEPKSIPSTSMLPTLDVGDRVIAEKVSYFFRKPEVSDIVIFKAPPILVEHGYSCADVFIKRIVASEGDWVEVCDGKLLVNDTVQAEDFVLEPIDYEMEPMFVPEGYVFVLGDNRNKSFDSHNWGPLPIKNIIGRSVFRYWPPSKVSDIIHHEQVSQKRAVDVS
Enzyme Length 367
Uniprot Accession Number Q9M9Z2
Absorption
Active Site ACT_SITE 214; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.; EC=3.4.21.89;
DNA Binding
EC Number 3.4.21.89
Enzyme Function FUNCTION: Cleaves the thylakoid-transfer domain from a chloroplast protein. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Region (1); Sequence conflict (2); Topological domain (1); Transit peptide (2); Transmembrane (1)
Keywords Chloroplast;Hydrolase;Membrane;Plastid;Protease;Reference proteome;Thylakoid;Transit peptide;Transmembrane;Transmembrane helix
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane; Single-pass membrane protein. Note=located in the non-appressed lamellae of the thylakoid network. {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 12185496; 16895613; 18775970; 22087276; 27247031;
Motif
Gene Encoded By
Mass 40,150
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda