| IED ID | IndEnz0002001410 |
| Enzyme Type ID | protease001410 |
| Protein Name |
Metalloprotease TIKI homolog EC 3.4.-.- |
| Gene Name | C05G5.5 |
| Organism | Caenorhabditis elegans |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis elegans |
| Enzyme Sequence | MTFYILVVSLYLSLFLVTVVQSDCDTDVEQRERNIFLWSVKHPQFASSQGYLFGTIHVPFTEVWKEVSDRVRDAFAVSDTVLLEIDLHDEATIHELIACKNLAYDETVHSYLSIELLERIEKIMEYLRSSFLAWAQKQNPRDTKKIKHAEDIYNNIIGDWWRKRPIWLLFLLYQMCENVFEKSSSPLLDLYIAQRATDEKKTIIPIETAEEQCNPVVSVSTNEIIFAIEHTVHYFEDKILDNPSKDNESRSSLKELVEHYKCGTLKEDMFDKDGMSIIDYATGTTERFKADEINKKLKQDIFVKRNLRMAKRIEKILKGRNSNTVFSAIGAGHFFGSSSVLTYLEESGFIVQKLKNTDVIQPLRSPYRQTAKFKRVWTKETAVRRKSIIIEEVAPSSSRIARLWLVPCIFLLHSIFAIFP |
| Enzyme Length | 420 |
| Uniprot Accession Number | Q17678 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.-.- |
| Enzyme Function | FUNCTION: Metalloprotease. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Alternative sequence (2); Chain (1); Glycosylation (1); Signal peptide (1); Topological domain (2); Transmembrane (1) |
| Keywords | Alternative splicing;Glycoprotein;Hydrolase;Membrane;Metal-binding;Metalloprotease;Protease;Reference proteome;Signal;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..22; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 17164286; 19123269; 19343510; 20439776; 21177967; 22347378; 22560298; 23800452; 25487147; |
| Motif | |
| Gene Encoded By | |
| Mass | 48,815 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |