Detail Information for IndEnz0002001440
IED ID IndEnz0002001440
Enzyme Type ID protease001440
Protein Name Regulator of RpoS
Gene Name rssB hnr SF1235 S1321
Organism Shigella flexneri
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Gammaproteobacteria Enterobacterales Enterobacteriaceae Shigella Shigella flexneri
Enzyme Sequence MTQPLVGKQILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDALELLGGFTPDLMICDIAMPRMNGLKLLEHIRNRGDQTPVLVISATENMADIAKALRLGVEDVLLKPVKDLNRLREMVFACLYPSMFNSRVEEEERLFRDWDAMVDNPAAAAKLLQELQPPVQQVISHCRVNYRQLVAADKPGLVLDIAALSENDLAFYCLDVTRAGHNGVLAALLLRALFNGLLQEQLAHQNQRLPELGALLKQVNHLLRQANLPGQFPLLVGYYHRELKNLILVSAGLNATLNTGEHQVQISNGVPLGTLGNAYLNQLSQRCDAWQCQIWGTGGRLRLMLSAE
Enzyme Length 337
Uniprot Accession Number P0AEV3
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. {ECO:0000255|HAMAP-Rule:MF_00958}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Domain (1); Modified residue (1)
Keywords Phosphoprotein;Reference proteome;Stress response
Interact With
Induction
Subcellular Location
Modified Residue MOD_RES 58; /note=4-aspartylphosphate; /evidence=ECO:0000255|HAMAP-Rule:MF_00958
Post Translational Modification PTM: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS. {ECO:0000255|HAMAP-Rule:MF_00958}.
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 37,302
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda