Detail Information for IndEnz0002001459
IED ID IndEnz0002001459
Enzyme Type ID protease001459
Protein Name Vacuolar membrane protease
EC 3.4.-.-
FXNA-related family protease 1
Gene Name SNOG_05559
Organism Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta dothideomyceta Dothideomycetes Pleosporomycetidae Pleosporales Pleosporineae Phaeosphaeriaceae Parastagonospora Phaeosphaeria nodorum (Glume blotch fungus) (Parastagonospora nodorum) Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum)
Enzyme Sequence MARLNPLSFTPGPVIFFTCAVYIALFAALLTVHLRVPDYPSKTPDGVNLTQAWSDLEKITRRFHPYNSHANDDVRDYLLTRVKSIIASKKLGGDQVELIDDNESNATFSSGSTTVYFEGTNIIVAIRGSEDDEPYHSPQSSPPGERRLDNGGVLVNAHYDSVSSGYGATDDGVGVVTVLQLLSYFTESKNWPKRTVILLLNNGEEDFLNGAKAFMRHPISQIAHTFVNLEGAGAGGRATMFRSTDTEVTRYYKASSHPFASVVSGDGFKKRLIRSETDYKVFYEELGLRGLDIAFMEPRARYHTVEDSTRETSLNSVWHMLSAAIATTSGLASDTSEQFSGSEDEHEPYTGKVKTGHGTDAVWFDLFGKVFVVFQLHTMFALCVTLLVVAPLFLIGLTFGLSKADKNYLFARKAYMYSSDDDHPVHLYGWRGFFRFPIVFSIATAVVVGLAYLMVRLNPLILYSSPYAVWSMMLSAWFSVAWFFSRGASAMRPSALQRMYALIWLFAGSFALLAFVTVLSNNYQVAGGYFALFYFAGIFLALVLSYLELFFAPTKTAFARYSAQGDEPVSRPLTGTTTAARSEEPPIADDDATETTSLLRGDRRSFARHSGRRDSIDDENGNRDEEPVQLDLKQPYPGEQDWSGKLPGWLWLLQLLLVAPIVVILVGQIALLLTSALHQTPADGNSSLFVYLAFALLTTLLLAPIGPFIHRFTWHVPTFVFLVCVATVIYNLVAFPFSREHRLKVYFVQQVDLATGNNRVSLTGVDGYVQRIVADLPSAQGEQINCTTPEAANRKELMTCTWPGLPAQVVTRASRFSNKTDTDGWLDFSITTSNKTNEATISVAGQNTRACRIVVDSHHSGVTNVTVAGAVSDPRFKAVGETGSREIRLWHREWSHPWNVSVTWPRENSKPSGRIICLWSDANAGDIPAFDEVQHYLPVWAIPSKISDGLVEGFKYFQV
Enzyme Length 959
Uniprot Accession Number Q0URQ5
Absorption
Active Site ACT_SITE 204; /note=Proton acceptor; /evidence=ECO:0000250|UniProtKB:P80561
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.-.-
Enzyme Function FUNCTION: May be involved in vacuolar sorting and osmoregulation. {ECO:0000250|UniProtKB:P38244}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Compositional bias (1); Glycosylation (9); Metal binding (6); Region (3); Site (1); Topological domain (10); Transmembrane (9)
Keywords Glycoprotein;Hydrolase;Membrane;Metal-binding;Metalloprotease;Protease;Reference proteome;Transmembrane;Transmembrane helix;Vacuole;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000250|UniProtKB:P38244}; Multi-pass membrane protein {ECO:0000255}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 106,393
Kinetics
Metal Binding METAL 158; /note=Zinc 1; catalytic; /evidence=ECO:0000250|UniProtKB:P80561; METAL 170; /note=Zinc 1; catalytic; /evidence=ECO:0000250|UniProtKB:P80561; METAL 170; /note=Zinc 2; catalytic; /evidence=ECO:0000250|UniProtKB:P80561; METAL 205; /note=Zinc 2; catalytic; /evidence=ECO:0000250|UniProtKB:P80561; METAL 230; /note=Zinc 1; catalytic; /evidence=ECO:0000250|UniProtKB:P80561; METAL 303; /note=Zinc 2; catalytic; /evidence=ECO:0000250|UniProtKB:P80561
Rhea ID
Cross Reference Brenda