Detail Information for IndEnz0002001464
IED ID IndEnz0002001464
Enzyme Type ID protease001464
Protein Name Vacuolar membrane protease
EC 3.4.-.-
FXNA-related family protease 1
Gene Name PTT_06479
Organism Pyrenophora teres f. teres (strain 0-1) (Barley net blotch fungus) (Drechslera teres f. teres)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta dothideomyceta Dothideomycetes Pleosporomycetidae Pleosporales Pleosporineae Pleosporaceae Pyrenophora Pyrenophora teres Pyrenophora teres f. teres Pyrenophora teres f. teres (strain 0-1) (Barley net blotch fungus) (Drechslera teres f. teres)
Enzyme Sequence MARYNPFSFTPGPVVFFTTVIYVGLFAALLVTHLTVPDYPSDPPAGINLTEAWADLEHITRRFHPYNSHANDHVREYLLSRIQGIVATKHLDGSQVEIIDDLTSNATFSSGATSVYFEGTNIIVAIRGSEDDEPFNSTDRRPNNGGVLVNAHYDSVSSGYGATDDGVGVVTVLQLLSYFTESHNWPKRTIILLLNNGEEDFLNGAKAFMRNPISRVPHTFVNLEGAGAGGRATLFRSTDTEVTRFYSKSKYPFGTVVSGDGFKKGLIRSETDYRVFHSDLGLRGLDIAFMEPRARYHTVEDSTRETSMNSLWHMLSAALASTSGLAAVTGEEFSGSESLDNGRVNAGRGSDGVWFDLFGRVFVVFQLHTLFALCVTLLVVAPITLIGLTFGLSKADKNYLLARKAFVYSSDDDNPVQLYGWRGFFRFPIIFISATAVVVALAYLLVRFNAFIIYSSPFAVWSMMLSAWFFVAWFFSRGADAMRPSALQRMYALIWLFIGSFVLLTIVTVFVNNYQVVAGYPALFYFAVVFVAIMLSYLELFFAPTKSAYARHFEHDANSRRNSDSASRPLTGSTTAARSDDRPVADDDATEITSLLRGDRRGFTRYGSRRDSASEGGEDQAQGSQRLDLGNVYPGEQEWSGKLPSWIWIIQLLLLAPLVIVLVGQVALLLTSALYQTPSDGNSPLFIYLAIAALSVLLLAPTGPFIHRFTYHVPTFLFLVCLGTVIYNLVAFPFSRDHRLKVYFVQRVNCETGANTVSLTGLDSYVQRIVGELPSAQDQPLNCTTPDVATRKELKTCEWEGLPAKVVPNAAGAAPFGNETNTGRWLEYSIHKGNRSNKATMLVVGLNTRACRIVFDSPISGLAVTGAVSDPRFKPVGAAGSREVRLWHREFGQPWNVGLTWDAEEHAKLSGRVVCLWSDANTGSIPAFDEVQHYLPVWAIPSKISDGLVEGFKRFEI
Enzyme Length 957
Uniprot Accession Number E3RFJ1
Absorption
Active Site ACT_SITE 198; /note=Proton acceptor; /evidence=ECO:0000250|UniProtKB:P80561
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.-.-
Enzyme Function FUNCTION: May be involved in vacuolar sorting and osmoregulation. {ECO:0000250|UniProtKB:P38244}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Compositional bias (1); Glycosylation (6); Metal binding (6); Region (2); Site (1); Topological domain (10); Transmembrane (9)
Keywords Glycoprotein;Hydrolase;Membrane;Metal-binding;Metalloprotease;Protease;Reference proteome;Transmembrane;Transmembrane helix;Vacuole;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000250|UniProtKB:P38244}; Multi-pass membrane protein {ECO:0000255}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 105,701
Kinetics
Metal Binding METAL 152; /note=Zinc 1; catalytic; /evidence=ECO:0000250|UniProtKB:P80561; METAL 164; /note=Zinc 1; catalytic; /evidence=ECO:0000250|UniProtKB:P80561; METAL 164; /note=Zinc 2; catalytic; /evidence=ECO:0000250|UniProtKB:P80561; METAL 199; /note=Zinc 2; catalytic; /evidence=ECO:0000250|UniProtKB:P80561; METAL 224; /note=Zinc 1; catalytic; /evidence=ECO:0000250|UniProtKB:P80561; METAL 297; /note=Zinc 2; catalytic; /evidence=ECO:0000250|UniProtKB:P80561
Rhea ID
Cross Reference Brenda