| IED ID | IndEnz0002001516 |
| Enzyme Type ID | protease001516 |
| Protein Name |
Tripeptidyl-peptidase 2 EC 3.4.14.10 Tripeptidyl-peptidase II TPPII |
| Gene Name | TPP2 Os02g0664300 LOC_Os02g44520 P0461B08.4-1 P0461B08.4-2 |
| Organism | Oryza sativa subsp. japonica (Rice) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae Liliopsida Petrosaviidae commelinids Poales Poaceae BOP clade Oryzoideae Oryzeae Oryzinae Oryza Oryza sativa (Rice) Oryza sativa subsp. japonica (Rice) |
| Enzyme Sequence | MWHLRGRSSVTAAAAAALHKPVAHLRLLLAVSAWSVPAAASNVAAASTTTRGGPSPSAGVAPRAMPSSSSSPPSAAEGTTAAAGGFRLTEPSFLESLMPKKEIGVDRFLAAHPEYDGRGALIAIFDSGVDPAAAGLQTTSDGKPKILDVIDCTGSGDVDTSKVVKADDDGSIVGASGTHLTINPSWKNPSQEWHVGCKLVYELFTDTLTSRLKKERKKKWDEHNQEAISEALKQLNEFEKKHSKSDDAKQKMAREDLQSRLEYLRKQAEGYDDRGPVIDIVAWHDGDVWRVAVDTQGLEGNKNCGKLADFVPLTNYRLERKFGIFSKLDACSFVANIYDDGNLVSIVTDCSPHATHVAGIAAAFHPDEPLLNGVAPGAQLISCKIGDTRLGSMETGTGLVRALIAAVEHKCDLINMSYGEPTLLPDYGRFIDLASEVVDKHRIIFISSAGNNGPALNTVGAPGGTSSSIIGVGAYVSPAMAAGAHCVVQAPAEGMEYTWSSRGPTADGDLGVSISAPGGAVAPVPTWTLQSRMLMNGTSMSSPSACGGVALLVSAMKAEGIPLSPYTVRKAIENTAASISDVPEEKLTTGHGLLQVDRAFEYAQQAKELPLVSYRISINQVGKPTSKLRGIYLRGSNTCRQTSEWTVQLDPKFHEDASNMEQLVPFEECLQLHSTDSSVIKIPEYIMVTNNGRTFNIVVNPVNISSGLHYYEVYGIDCKAPWRGPIFRVPITVIKPIALSGEPPALTLSNLSFKSGHIERRFINVPIGASWVEVTMRTSAFDTPRRFFLDTVQICPLKRPIKWEAVVTFSSPSLKNFSFPVEGGLTLELSIAQFWSSGIASHEPTCVDFEIVFHGISVDQKIIGLDGSEAPVRVVARSLLASERLVPVATLNKVKTPYRPVESNLCSLPPSRDRLPSGKQIIALTLTYKFKLEDGAEIKPRVPLLNNRIYDNKFESQYYRISDSNKCVYSSGDVYPNYVKLSKGEYTLQLYIRHDNVQLLEKLKQLVLFIERKLEKKDFIQLSFYSEPDGPTVGNGTFKSSILVPGEPEAFYVGPPSREKLPKNVLPGSVLVGSITYGAVSSFSKKDDQNQHAPASYSISYLIPPSKVDNDKEKGVSSGRKSISERLDDEVRDTKIKFLSGFNQETEDDKSSWTALVASLKPEYPKYTPLLAKILECIVQKATSDDKFSHQKEIIAAADEVVDSIDKEDLAKSLSLKPDPEDEEAQKNKKKMEETRDQLADALYQKGLALAEIESLKTDESTEASAKDVFEENYKELIKWVDAKTTKYGSLTVLRERRCGRLGTALKVLNDMIQDDSEQPKKRLYDLKIQLIEEIGWVHVSAYEKQWMHVRFPPSLPPF |
| Enzyme Length | 1359 |
| Uniprot Accession Number | Q6ESI7 |
| Absorption | |
| Active Site | ACT_SITE 126; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240; ACT_SITE 353; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240; ACT_SITE 539; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Release of an N-terminal tripeptide from a polypeptide.; EC=3.4.14.10; Evidence={ECO:0000250|UniProtKB:F4JVN6}; |
| DNA Binding | |
| EC Number | 3.4.14.10 |
| Enzyme Function | FUNCTION: Serine protease that may function in the proteasome pathway. {ECO:0000250|UniProtKB:F4JVN6}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Compositional bias (1); Domain (1); Erroneous gene model prediction (1); Region (1); Sequence conflict (3) |
| Keywords | Aminopeptidase;Hydrolase;Protease;Reference proteome;Serine protease |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 148,633 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |