IED ID | IndEnz0002001521 |
Enzyme Type ID | protease001521 |
Protein Name |
Zinc metalloprotease TldD homolog EC 3.4.-.- |
Gene Name | tldD SSO0660 |
Organism | Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) |
Taxonomic Lineage | cellular organisms Archaea TACK group Crenarchaeota Thermoprotei Sulfolobales Sulfolobaceae Saccharolobus Saccharolobus solfataricus (Sulfolobus solfataricus) Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) |
Enzyme Sequence | MFKYIKKAEELGASFADIRYERVIANEVTITEDRKYVSHGVDEGYSIRVIYNRNWGFKATDKITENEIEDTINHIYGDERVNIVYLPSKHDTIKIGKDINKNEEEKINDLHKVASQVNTLHPSIKSYSIKYYDEIFHKEYYSSEDREIIADGSSSSLSILVVAREGDVTVEVSEILSTQMGYIFDVFDINQVLANLQKRIINQLKGSTPKAGEYPVILAPEVVGIFTHEAIGHLSEADVTLNGSLYKLRNKRIGDEFLNISDLPAMDHPQSSLVYYDDEGVEGREVKIIENGILKEFMTDRYYSAYLGQPPTGNARAQSYRNFSLIRMRNTYMKPGDASLNELFEGIKEGYYLVSPIGGETSSNGTFQFAIQEGYRVENSEIKEPLRNIGISGNTISTLNAIEMISKDFGMSSGFCEKNGQTVQVSNGGPHIKVKKLKVGGYV |
Enzyme Length | 443 |
Uniprot Accession Number | Q7LXP6 |
Absorption | |
Active Site | |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | 3.4.-.- |
Enzyme Function | FUNCTION: Zinc metalloprotease. Able to degrade azocasein in vitro. {ECO:0000269|PubMed:22950735}. |
Temperature Dependency | BIOPHYSICOCHEMICAL PROPERTIES: Temperature dependence: Optimum temperature is 55-65 degrees Celsius. {ECO:0000269|PubMed:22950735}; |
PH Dependency | BIOPHYSICOCHEMICAL PROPERTIES: pH dependence: Optimum pH is 7.0. {ECO:0000269|PubMed:22950735}; |
Pathway | |
nucleotide Binding | |
Features | Chain (1); Motif (1); Mutagenesis (4) |
Keywords | Hydrolase;Metalloprotease;Protease;Reference proteome |
Interact With | |
Induction | |
Subcellular Location | |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | MOTIF 228..233; /note=HEAIGH motif |
Gene Encoded By | |
Mass | 49,882 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda | 3.4.24.B29; |