Detail Information for IndEnz0002001521
IED ID IndEnz0002001521
Enzyme Type ID protease001521
Protein Name Zinc metalloprotease TldD homolog
EC 3.4.-.-
Gene Name tldD SSO0660
Organism Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Taxonomic Lineage cellular organisms Archaea TACK group Crenarchaeota Thermoprotei Sulfolobales Sulfolobaceae Saccharolobus Saccharolobus solfataricus (Sulfolobus solfataricus) Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Enzyme Sequence MFKYIKKAEELGASFADIRYERVIANEVTITEDRKYVSHGVDEGYSIRVIYNRNWGFKATDKITENEIEDTINHIYGDERVNIVYLPSKHDTIKIGKDINKNEEEKINDLHKVASQVNTLHPSIKSYSIKYYDEIFHKEYYSSEDREIIADGSSSSLSILVVAREGDVTVEVSEILSTQMGYIFDVFDINQVLANLQKRIINQLKGSTPKAGEYPVILAPEVVGIFTHEAIGHLSEADVTLNGSLYKLRNKRIGDEFLNISDLPAMDHPQSSLVYYDDEGVEGREVKIIENGILKEFMTDRYYSAYLGQPPTGNARAQSYRNFSLIRMRNTYMKPGDASLNELFEGIKEGYYLVSPIGGETSSNGTFQFAIQEGYRVENSEIKEPLRNIGISGNTISTLNAIEMISKDFGMSSGFCEKNGQTVQVSNGGPHIKVKKLKVGGYV
Enzyme Length 443
Uniprot Accession Number Q7LXP6
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.-.-
Enzyme Function FUNCTION: Zinc metalloprotease. Able to degrade azocasein in vitro. {ECO:0000269|PubMed:22950735}.
Temperature Dependency BIOPHYSICOCHEMICAL PROPERTIES: Temperature dependence: Optimum temperature is 55-65 degrees Celsius. {ECO:0000269|PubMed:22950735};
PH Dependency BIOPHYSICOCHEMICAL PROPERTIES: pH dependence: Optimum pH is 7.0. {ECO:0000269|PubMed:22950735};
Pathway
nucleotide Binding
Features Chain (1); Motif (1); Mutagenesis (4)
Keywords Hydrolase;Metalloprotease;Protease;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif MOTIF 228..233; /note=HEAIGH motif
Gene Encoded By
Mass 49,882
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda 3.4.24.B29;