Detail Information for IndEnz0002001567
IED ID IndEnz0002001567
Enzyme Type ID protease001567
Protein Name Subtilisin-like protease 7
EC 3.4.21.-
Gene Name SUB7 MCYG_02345
Organism Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Microsporum Arthroderma otae (Microsporum canis) Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
Enzyme Sequence MGFITKAIPLALAAMSVVNGAEILETRAGVQTLADKYIVIMNDGVTEKAFDSHRSWVNRTHRRRLVRRGAKAMGGMKHTYKFPTGMKGYSGHFDEDMINQIAKHSDVKYIERDARVQINAITEQDNVPSWGLARVGSREAGGSTYYYDSTAGEGSTAYIIDTGTDIEHEEFEGRATWGSNFVDDMDMDCNGHGTHVSGTVGGATFGVAKKSNIVAVKVLDCNGSGSNSGVIMGMEWATNDAKKKGADKAVANMSLGGAFSQASNDAAAAIANGGVFLAVAAGNDNVDAANSSPASEPSICTVAASTEQDGKADFSNFGQVVDVYAPGDSITSAKPGGGSQVLSGTSMATPHVAGLAAYFIGLGMPGGPGLCDTIKQKAIDAIANPGAGTTGKLINNGSGK
Enzyme Length 400
Uniprot Accession Number C5FJA5
Absorption
Active Site ACT_SITE 161; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240; ACT_SITE 192; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240; ACT_SITE 346; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.21.-
Enzyme Function FUNCTION: Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Chain (1); Domain (2); Glycosylation (3); Propeptide (1); Signal peptide (1)
Keywords Glycoprotein;Hydrolase;Protease;Reference proteome;Secreted;Serine protease;Signal;Virulence;Zymogen
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..20; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 41,380
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda