| IED ID | IndEnz0002001590 |
| Enzyme Type ID | protease001590 |
| Protein Name |
Thymus-specific serine protease EC 3.4.-.- Serine protease 16 |
| Gene Name | Prss16 Tssp |
| Organism | Mus musculus (Mouse) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Myomorpha (mice and others) Muroidea Muridae Murinae Mus Mus Mus musculus (Mouse) |
| Enzyme Sequence | MAVKAPWLGFLLLVSLWGLSTPALLLRRLREHIQKFQESSSLHPGFGLGHGPGAVPKQGWLEQPLDPFNASDRRTFLQRYWVNDQHRTGQDVPVFLHIGGEGSLGPGSVMAGHPAALAPAWGALVISLEHRFYGLSMPAGGLDLALLRYLSSRHALADVASARQALSGLLNVSSSSPWICFGGSYAGSLATWARLKFPHLVFAAVASSAPLSAVVDFSAYNQVVARSLTQVAIGGSLECLAAASTAFTEVERLLRAGPAAQAVLREELGACGSLDLTEDQAELLGALQALVGGTVQYDGQAGAPLSVRQLCGLLLGKWGNRSRSTPYLGLRRAVQIVLRSMGQKCLSFSRAETVAQLSNTEPQVSGVGDRQWLYQTCTEFGFYVTCEGLQCPFSQLPALPFQLELCEQVFGLSPASVAQAVAQTNSYYGGQSPGATQVLFVNGDTDPWHVLSVTQDLGLSEPALLIPSASHCFDMAPMRPSDSPSLRLGRQKISQQLQDWLKDIKKSQS |
| Enzyme Length | 509 |
| Uniprot Accession Number | Q9QXE5 |
| Absorption | |
| Active Site | ACT_SITE 184; /note=Charge relay system; /evidence=ECO:0000255; ACT_SITE 446; /note=Charge relay system; /evidence=ECO:0000255; ACT_SITE 471; /note=Charge relay system; /evidence=ECO:0000255 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.-.- |
| Enzyme Function | FUNCTION: Protease that may play a role in T-cell development. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Glycosylation (3); Signal peptide (1) |
| Keywords | Cytoplasmic vesicle;Glycoprotein;Hydrolase;Protease;Reference proteome;Serine protease;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasmic vesicle. Note=Vesicular, either lysosomal or endosomal. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..22; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 10527559; 11003393; 12144812; 12466851; 15632078; 19283781; 21173102; 21505262; 21677750; 24194600; 25543139; 25884569; 29061767; |
| Motif | |
| Gene Encoded By | |
| Mass | 54,523 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |