IED ID |
IndEnz0002001645 |
Enzyme Type ID |
protease001645 |
Protein Name |
Probable 26S proteasome regulatory subunit rpn3
|
Gene Name |
rpn3 SPBC119.01 SPBPJ4664.07 |
Organism |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Fungi
Dikarya
Ascomycota
Taphrinomycotina
Schizosaccharomycetes
Schizosaccharomycetales
Schizosaccharomycetaceae
Schizosaccharomyces
Schizosaccharomyces pombe (Fission yeast)
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
|
Enzyme Sequence |
MIDDQRDMQVDSVNQEENVDSGETKQNTVTEVPRTVLQDVEANIAALMQATKQRDPRLVYRSLRTTSNICHRLNADVLGQLIKKYYSFDNSLKNELLELIDMPQNGDDSSTSITNGNGNTIFPEVDMYLQLLLSMTLYYNEKYEVGAEYIKKVIARLQSYDRRTLDQIAAKLYFYYILFFEKCNRSVECRNTLLSVHRTASLRHDSETQAMVLTLLLRNYIQFNLYDQADRLVSKTSFLTNASNNLAIRYQYYLGRIRAIQLDYTTAHEHLVSAIRKAPNTVYAVQFLEAVYKLHIVVQLLMGEIPERRIFRQKSLEKTLVPYLRISQAVRIGDLCAFTDALSKYEAEFRFDGLYTLICRLRHTVIKTGLRMISLSYSRISLRDVCIKLGLDSEESAEYIVAKGIRDGVIDASIDHSNAFMASNEAMDIYSTEQPQQAFHERIQFCLALHNDSIKSMRYPMDAHKSELEGVEEARRRMDKEMAEADLDDDEPDLGEF |
Enzyme Length |
497 |
Uniprot Accession Number |
O42897 |
Absorption |
|
Active Site |
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Activity Regulation |
|
Binding Site |
|
Calcium Binding |
|
catalytic Activity |
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DNA Binding |
|
EC Number |
|
Enzyme Function |
FUNCTION: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. {ECO:0000250}. |
Temperature Dependency |
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PH Dependency |
|
Pathway |
|
nucleotide Binding |
|
Features |
Chain (1); Domain (1); Region (2) |
Keywords |
Proteasome;Reference proteome |
Interact With |
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Induction |
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Subcellular Location |
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Modified Residue |
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Post Translational Modification |
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Signal Peptide |
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Structure 3D |
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Cross Reference PDB |
- |
Mapped Pubmed ID |
16149916;
20473289;
21712547;
23697806;
25720772;
30726745;
|
Motif |
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Gene Encoded By |
|
Mass |
57,346 |
Kinetics |
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Metal Binding |
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Rhea ID |
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Cross Reference Brenda |
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