| IED ID | IndEnz0002001733 |
| Enzyme Type ID | protease001733 |
| Protein Name |
Senescence-specific cysteine protease SAG39 EC 3.4.22.- Cysteine proteinase SAG39 Protein SENESCENCE-ASSOCIATED GENE 39 |
| Gene Name | SAG39 Os04g0206300 OsJ_13822 OSJNBa0052O21.11 |
| Organism | Oryza sativa subsp. japonica (Rice) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae Liliopsida Petrosaviidae commelinids Poales Poaceae BOP clade Oryzoideae Oryzeae Oryzinae Oryza Oryza sativa (Rice) Oryza sativa subsp. japonica (Rice) |
| Enzyme Sequence | MAMAKALLFAILGCLCLCSAVLAARELSDDAAMAARHERWMAQYGRVYRDDAEKARRFEVFKANVAFIESFNAGNHNFWLGVNQFADLTNDEFRWMKTNKGFIPSTTRVPTGFRYENVNIDALPATVDWRTKGAVTPIKDQGQCGCCWAFSAVAAMEGIVKLSTGKLISLSEQELVDCDVHGEDQGCEGGLMDDAFKFIIKNGGLTTESNYPYAAADDKCKSVSNSVASIKGYEDVPANNEAALMKAVANQPVSVAVDGGDMTFQFYKGGVMTGSCGTDLDHGIVAIGYGKASDGTKYWLLKNSWGTTWGENGFLRMEKDISDKRGMCGLAMEPSYPTA |
| Enzyme Length | 339 |
| Uniprot Accession Number | Q7XWK5 |
| Absorption | |
| Active Site | ACT_SITE 147; /evidence=ECO:0000255|PROSITE-ProRule:PRU10088; ACT_SITE 282; /evidence=ECO:0000255|PROSITE-ProRule:PRU10089; ACT_SITE 303; /evidence=ECO:0000255|PROSITE-ProRule:PRU10090 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | FUNCTION: Cysteine protease that may have a developmental senescence specific cell death function during apoptosis, heavy metal detoxification, and hypersensitive response. {ECO:0000250|UniProtKB:Q9FJ47}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Signal peptide (1) |
| Keywords | Hydrolase;Protease;Reference proteome;Signal;Thiol protease;Vacuole |
| Interact With | |
| Induction | INDUCTION: Accumulates progressively during senescence with maximum levels at late senescence stages. Induced by abscisic acid (ABA), ethylene (ACC) and gibberellin (GA(3)). {ECO:0000269|PubMed:20439547}. |
| Subcellular Location | SUBCELLULAR LOCATION: Vacuole {ECO:0000250|UniProtKB:Q9FJ47}. Note=Localized in senescence-associated vacuoles (SAVs) with intense proteolytic activity that develop in the peripheral cytoplasm of mesophyll and guard cells. {ECO:0000250|UniProtKB:Q9FJ47}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..23; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 36,872 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |