Detail Information for IndEnz0002001733
IED ID IndEnz0002001733
Enzyme Type ID protease001733
Protein Name Senescence-specific cysteine protease SAG39
EC 3.4.22.-
Cysteine proteinase SAG39
Protein SENESCENCE-ASSOCIATED GENE 39
Gene Name SAG39 Os04g0206300 OsJ_13822 OSJNBa0052O21.11
Organism Oryza sativa subsp. japonica (Rice)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae Liliopsida Petrosaviidae commelinids Poales Poaceae BOP clade Oryzoideae Oryzeae Oryzinae Oryza Oryza sativa (Rice) Oryza sativa subsp. japonica (Rice)
Enzyme Sequence MAMAKALLFAILGCLCLCSAVLAARELSDDAAMAARHERWMAQYGRVYRDDAEKARRFEVFKANVAFIESFNAGNHNFWLGVNQFADLTNDEFRWMKTNKGFIPSTTRVPTGFRYENVNIDALPATVDWRTKGAVTPIKDQGQCGCCWAFSAVAAMEGIVKLSTGKLISLSEQELVDCDVHGEDQGCEGGLMDDAFKFIIKNGGLTTESNYPYAAADDKCKSVSNSVASIKGYEDVPANNEAALMKAVANQPVSVAVDGGDMTFQFYKGGVMTGSCGTDLDHGIVAIGYGKASDGTKYWLLKNSWGTTWGENGFLRMEKDISDKRGMCGLAMEPSYPTA
Enzyme Length 339
Uniprot Accession Number Q7XWK5
Absorption
Active Site ACT_SITE 147; /evidence=ECO:0000255|PROSITE-ProRule:PRU10088; ACT_SITE 282; /evidence=ECO:0000255|PROSITE-ProRule:PRU10089; ACT_SITE 303; /evidence=ECO:0000255|PROSITE-ProRule:PRU10090
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.22.-
Enzyme Function FUNCTION: Cysteine protease that may have a developmental senescence specific cell death function during apoptosis, heavy metal detoxification, and hypersensitive response. {ECO:0000250|UniProtKB:Q9FJ47}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Chain (1); Signal peptide (1)
Keywords Hydrolase;Protease;Reference proteome;Signal;Thiol protease;Vacuole
Interact With
Induction INDUCTION: Accumulates progressively during senescence with maximum levels at late senescence stages. Induced by abscisic acid (ABA), ethylene (ACC) and gibberellin (GA(3)). {ECO:0000269|PubMed:20439547}.
Subcellular Location SUBCELLULAR LOCATION: Vacuole {ECO:0000250|UniProtKB:Q9FJ47}. Note=Localized in senescence-associated vacuoles (SAVs) with intense proteolytic activity that develop in the peripheral cytoplasm of mesophyll and guard cells. {ECO:0000250|UniProtKB:Q9FJ47}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..23; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 36,872
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda