Detail Information for IndEnz0002001747
IED ID IndEnz0002001747
Enzyme Type ID protease001747
Protein Name Trypsin inhibitor 1
SFTI-1
Gene Name sfti1
Organism Helianthus annuus (Common sunflower)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae asterids campanulids Asterales Asteraceae Asteroideae Heliantheae alliance Heliantheae Helianthus Helianthus annuus (Common sunflower)
Enzyme Sequence MATTMAKLITLVVLAILAFVEVSVSGYKTSISTITIEDNGRCTKSIPPICFPDGRP
Enzyme Length 56
Uniprot Accession Number Q4GWU5
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Inhibits trypsin, cathepsin G, elastase, chymotrypsin and thrombin. Does not inhibit factor Xa. {ECO:0000269|PubMed:10390350}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Beta strand (3); Cross-link (1); Disulfide bond (1); Peptide (1); Propeptide (2); Signal peptide (1); Site (1)
Keywords 3D-structure;Direct protein sequencing;Disulfide bond;Protease inhibitor;Serine protease inhibitor;Signal
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification PTM: This is a cyclic peptide. {ECO:0000269|PubMed:10390350}.
Signal Peptide SIGNAL 1..25; /evidence=ECO:0000255
Structure 3D NMR spectroscopy (17); X-ray crystallography (17)
Cross Reference PDB 1JBL; 1JBN; 1O8Y; 1O8Z; 1SFI; 1T9E; 2AB9; 3P8F; 4ABI; 4ABJ; 4HGC; 4K1E; 4K8Y; 4KEL; 4XOJ; 6BVH; 6BVU; 6BVW; 6BVX; 6BVY; 6D3X; 6D3Y; 6D3Z; 6D40; 6Q1U; 6U22; 6U24; 6U7Q; 6U7R; 6U7S; 6U7U; 6U7X; 6VXY; 6VY8;
Mapped Pubmed ID 15667208; 21693064; 22374650; 24598736; 26212347; 27767076; 29605997; 30520638; 30668585; 31058493; 32270580;
Motif
Gene Encoded By
Mass 5,971
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda