| IED ID | IndEnz0002001771 |
| Enzyme Type ID | protease001771 |
| Protein Name |
Serine proteinase inhibitor 2 Serp-2 Serpin-2 |
| Gene Name | SERP2 SPI-2 m151R |
| Organism | Myxoma virus (strain Lausanne) (MYXV) |
| Taxonomic Lineage | Viruses Varidnaviria Bamfordvirae Nucleocytoviricota Pokkesviricetes Chitovirales Poxviridae Chordopoxvirinae Leporipoxvirus Myxoma virus Myxoma virus (strain Lausanne) (MYXV) |
| Enzyme Sequence | MELFKHFLQSTASDVFVSPVSISAVLAVLLEGAKGRTAAQLRLALEPRYSHLDKVTVASRVYGDWRLDIKPKFMQAVRDRFELVNFNHSPEKIKDDINRWVAARTNNKILNAVNSISPDTKLLIVAAIYFEVAWRNQFVPDFTIEGEFWVTKDVSKTVRMMTLSDDFRFVDVRNEGIKMIELPYEYGYSMLVIIPDDLEQVERHLSLMKVISWLKMSTLRYVHLSFPKFKMETSYTLNEALATSGVTDIFAHPNFEDMTDDKNVAVSDIFHKAYIEVTEFGTTAASCTYGCVTDFGGTMDPVVLKVNKPFIFIIKHDDTFSLLFLGRVTSPNY |
| Enzyme Length | 333 |
| Uniprot Accession Number | P68565 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Weak inhibitor of the interleukin-1-beta converting enzyme (ICE) and of granzyme B. Does not form a stable complex with ICE, but can for a stable complex with granzyme B. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Site (1) |
| Keywords | Host cytoplasm;Host-virus interaction;Inhibition of host caspases by virus;Modulation of host cell apoptosis by virus;Protease inhibitor;Reference proteome;Serine protease inhibitor |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 38,046 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |