Detail Information for IndEnz0002001773
IED ID IndEnz0002001773
Enzyme Type ID protease001773
Protein Name Serine proteinase inhibitor 2
Serp-2
Serpin-2
Gene Name SPI-2 RPXV175
Organism Rabbitpox virus (strain Utrecht) (RPV)
Taxonomic Lineage Viruses Varidnaviria Bamfordvirae Nucleocytoviricota Pokkesviricetes Chitovirales Poxviridae Chordopoxvirinae Orthopoxvirus Vaccinia virus Rabbitpox virus Rabbitpox virus (strain Utrecht) (RPV)
Enzyme Sequence MDIFREIASSMKGENVFISPASISSVLTILYYGANGSTAEQLSKYVEKEENMDKVSAQNISFKSINKVYGRYSAVFKDSFLRKIGDKFQTVDFTDCRTIDAINKCVDIFTEGKINPLLDEQLSPDTCLLAISAVYFKAKWLTPFEKEFTSDYPFYVSPTEMVDVSMMSMYGKAFNHASVKESFGNFSIIELPYVGDTSMMVILPDKIDGLESIEQNLTDTNFKKWCNSLEATFIDVHIPKFKVTGSYNLVDTLVKSGLTEVFGSTGDYSNMCNLDVSVDAMIHKTYIDVNEEYTEAAAATSVLVADCASTVTNEFCADHPFIYVIRHVDGKILFVGRYCSPTTNC
Enzyme Length 345
Uniprot Accession Number P42926
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: May be involved in the regulation of the complement cascade. Involved in red pock formation.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Site (1)
Keywords Host cytoplasm;Host-virus interaction;Inhibition of host caspases by virus;Modulation of host cell apoptosis by virus;Protease inhibitor;Serine protease inhibitor
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000305}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 38,548
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda